Alpinumisoflavone
Appearance
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IUPAC name
4′,5-Dihydroxy-6′′,6′′-dimethyl-6′′H-pyrano[3′′,2′′:6,7]isoflavone
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Systematic IUPAC name
5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:5,4-b′]dipyran-4-one | |
Other names
5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethylpyrano[3,2-g]chromen-4-one
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C20H16O5 | |
Molar mass | 336.33 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Alpinumisoflavone is a pyranoisoflavone, a type of isoflavone. It can be found in the bark of Rinorea welwitschii.[1] It can also be found in the molluscicide plant Millettia thonningii and is thought to be an antischistosomal agent[2] since it has been shown to kill the snails which transmit the schistosomiasis and also the larvae of the parasite itself.[3]
References
[edit]- ^ Stewart, M.; Bartholomew, B.; Currie, F.; Abbiw, D.K.; Latif, Z.; Sarker, S.D.; Nash, R.J. (2000). "Pyranoisoflavones from Rinorea welwitschii". Fitoterapia. 71 (5): 595–597. doi:10.1016/S0367-326X(00)00210-0. PMID 11449519.
- ^ Perrett, S.; Whitfield, P.J.; Sanderson, L.; Bartlett, A. (1995). "The plant molluscicide Millettia thonningii (Leguminosae) as a topical antischistosomal agent". Journal of Ethnopharmacology. 47 (1): 49–54. doi:10.1016/0378-8741(95)01253-a. PMID 7564421.
- ^ Perrett, Sheena; Whitfield, Philip J. (1995). "Aqueous degradation of isoflavonoids in an extract of Millettia thonningii (Leguminosae) which is larvicidal towards schistosomes". Phytotherapy Research. 9 (6): 401–404. doi:10.1002/ptr.2650090603. S2CID 85035592.