Actino-pnp RNA motif
| Actino-pnp RNA | |
|---|---|
 Consensus secondary structure of Actino-pnp RNAs | |
| Identifiers | |
| Symbol | Actino-pnp |
| Rfam | RF01688 |
| Other data | |
| Domain(s) | Bacteria |
| SO | 0005836 |
| PDB structures | PDBe |
The Actino-pnp RNA motif is a conserved structure found in Actinomycetota that is apparently in the 5' untranslated regions of genes predicted to encode exoribonucleases.[1] The RNA element's function is likely analogous to an RNA structure found upstream of polynucleotide phosphorylase genes in E. coli and related enterobacteria.[2] In this latter system, the polynucleotide phosphorlyase gene regulates its own expression levels by a feedback mechanism that involves its activity upon the RNA structure. However, the E. coli RNA appears to be structurally unrelated to the Actino-pnp motif.
References
[edit]- ^ Weinberg Z, Wang JX, Bogue J, Yang J, Corbino K, Moy RH, Breaker RR (2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes". Genome Biology. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
- ^ Jarrige AC, Mathy N, Portier C (December 2001). "PNPase autocontrols its expression by degrading a double-stranded structure in the pnp mRNA leader". The EMBO Journal. 20 (23): 6845–6855. doi:10.1093/emboj/20.23.6845. PMC 125756. PMID 11726520.
External links
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