Absorption rate constant

The absorption rate constant K_a is a value used in pharmacokinetics to describe the rate at which a drug enters into the system. It is expressed in units of time⁻¹.^[1] The K_a is related to the absorption half-life (t_1/2a) per the following equation: K_a = ln(2) / t_1/2a.^[1]

K_a values can typically only be found in research articles.^[2] This is in contrast to parameters like bioavailability and elimination half-life, which can often be found in drug and pharmacology handbooks.^[2]

References

^ ^a ^b John E. Murphy (1 July 2016). Clinical Pharmacokinetics. ASHP. pp. 26–. ISBN 978-1-58528-538-9.
^ ^a ^b Miles Hacker; William S. Messer; Kenneth A. Bachmann (19 June 2009). Pharmacology: Principles and Practice. Academic Press. pp. 257–. ISBN 978-0-08-091922-5.

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[Murphy2016-1] John E. Murphy (1 July 2016). Clinical Pharmacokinetics. ASHP. pp. 26–. ISBN 978-1-58528-538-9.

[HackerMesser2009-2] Miles Hacker; William S. Messer; Kenneth A. Bachmann (19 June 2009). Pharmacology: Principles and Practice. Academic Press. pp. 257–. ISBN 978-0-08-091922-5.

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