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Abieta-7,13-dien-18-al dehydrogenase

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Abieta-7,13-dien-18-al dehydrogenase
Identifiers
EC no.1.2.1.74
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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Abieta-7,13-dien-18-al dehydrogenase (EC 1.2.1.74, abietadienal dehydrogenase (ambiguous)) is an enzyme with systematic name abieta-7,13-dien-18-al:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

abieta-7,13-dien-18-al + H2O + NAD+ abieta-7,13-dien-18-oate + NADH + H+

This enzyme catalyses the last step of the pathway of abietic acid biosynthesis in Abies grandis.

References

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  1. ^ Funk C, Croteau R (January 1994). "Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis". Archives of Biochemistry and Biophysics. 308 (1): 258–66. doi:10.1006/abbi.1994.1036. PMID 8311462.
  2. ^ Funk C, Lewinsohn E, Vogel BS, Steele CL, Croteau R (November 1994). "Regulation of Oleoresinosis in Grand Fir (Abies grandis) (Coordinate Induction of Monoterpene and Diterpene Cyclases and Two Cytochrome P450-Dependent Diterpenoid Hydroxylases by Stem Wounding)". Plant Physiology. 106 (3): 999–1005. doi:10.1104/pp.106.3.999. PMC 159624. PMID 12232380.
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