Aar small RNA
In molecular biology, the Aar small RNA is a small RNA (sRNA) produced by species of Acinetobacter. It was first discovered in Acinetobacter baylyi, and is located between the trpS and sucD genes.[1] TrpS encodes tryptophanyl-tRNA-synthetase II and sucD encodes succinyl-coA-synthetase subunit alpha.[2][3] Aar upregulates several mRNAs encoding proteins involved in amino acid metabolism.[4]
In Acinetobacter baumannii, Aar represses expression of the outer membrane protein CarO and the siderophore receptor BfnH : https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae668/7734169?login=true
See also
[edit]References
[edit]- ^ Schilling, D; Findeiss, S; Richter, AS; Taylor, JA; Gerischer, U (September 2010). "The small RNA Aar in Acinetobacter baylyi: a putative regulator of amino acid metabolism". Archives of Microbiology. 192 (9): 691–702. Bibcode:2010ArMic.192..691S. doi:10.1007/s00203-010-0592-6. PMID 20559624. S2CID 16709707.
- ^ Schimmel, PR; Söll, D (1979). "Aminoacyl-tRNA synthetases: general features and recognition of transfer RNAs". Annual Review of Biochemistry. 48: 601–648. doi:10.1146/annurev.bi.48.070179.003125. PMID 382994.
- ^ Buck, D; Guest, JR (June 15, 1969). "Overexpression and site-directed mutagenesis of the succinyl-CoA synthetase of Escherichia coli and nucleotide sequence of a gene (g30) that is adjacent to the suc operon". The Biochemical Journal. 260 (3): 737–747. doi:10.1042/bj2600737. PMC 1138739. PMID 2548486.
- ^ Schilling, D; Findeiss, S; Richter, AS; Taylor, JA; Gerischer, U (September 2010). "The small RNA Aar in Acinetobacter baylyi: a putative regulator of amino acid metabolism". Archives of Microbiology. 192 (9): 691–702. Bibcode:2010ArMic.192..691S. doi:10.1007/s00203-010-0592-6. PMID 20559624. S2CID 16709707.