ARMCX1

ARMCX1
Identifiers
Aliases	ARMCX1, ALEX1, GASP7, armadillo repeat containing, X-linked 1, armadillo repeat containing X-linked 1
External IDs	OMIM: 300362; MGI: 1925498; HomoloGene: 9589; GeneCards: ARMCX1; OMA:ARMCX1 - orthologs
Gene location (Human) Chr. X chromosome (human) Band Xq22.1 Start 101,550,547 bp End 101,554,700 bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X|X E3 Start 133,618,712 bp End 133,622,666 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium Epithelium of choroid plexus parietal pleura Brodmann area 23 right ventricle cartilage tissue visceral pleura tail of epididymis Skeletal muscle tissue of rectus abdominis glomerulus Top expressed in superior cervical ganglion pontine nuclei facial motor nucleus ventral tegmental area habenula dorsomedial hypothalamic nucleus medial dorsal nucleus inferior colliculi barrel cortex medial vestibular nucleus More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 51309 78248 Ensembl ENSG00000126947 ENSMUSG00000033460 UniProt Q9P291 Q9CX83 RefSeq (mRNA) NM_016608 NM_001166377 NM_001166378 NM_001166379 NM_001166380 NM_030066 RefSeq (protein) NP_057692 NP_001159849 NP_001159850 NP_001159851 NP_001159852 NP_084342 Location (UCSC) Chr X: 101.55 – 101.55 Mb Chr X: 133.62 – 133.62 Mb PubMed search
Wikidata
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Armadillo repeat-containing X-linked protein 1 is a protein that in humans is encoded by the ARMCX1 gene.

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.

External links

• Human ARMCX1 genome location and ARMCX1 gene details page in the UCSC Genome Browser.

Further reading

• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–337. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.