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ARL6IP6

From Wikipedia, the free encyclopedia
ARL6IP6
Identifiers
AliasesARL6IP6, AIP-6, PFAAP1, AIP6, ADP ribosylation factor like GTPase 6 interacting protein 6
External IDsOMIM: 616495; MGI: 1929507; HomoloGene: 11302; GeneCards: ARL6IP6; OMA:ARL6IP6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152522

NM_022989

RefSeq (protein)

NP_689735
NP_001336997
NP_001358901

NP_075365

Location (UCSC)n/aChr 2: 53.08 – 53.11 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

ADP ribosylation factor like GTPase 6 interacting protein 6 is a protein that in the humans is encoded by the ARL6IP6 gene.[4][5][6] It spans from 152,717,893 to 152,761,253 on the plus strand.

Gene

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General properties

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ARL6IP6 Also known as Phosphonoformate Immuno-Associated Protein 1. It has 43,361 bases and 11 exons and is located on the long arm of chromosome 2, at 2q23.3 in humans.[7] In humans there are three upstream genes (PRPF40A, FMNL2 and STAM2) and three downstream genes (GALNT13, KCNJ3, NR4A2) that define the identity of this genomic region.[8]

Promoter

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Expression

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References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026960Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ National Center for Biotechnology Information. "ADP ribosylation factor like GTPase 6 interacting protein 6". NCBI Gene.
  5. ^ "UniProtKB - Q8N6S5 (AR6P6_HUMAN)". uniprot.org. UniProt.
  6. ^ "ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. National Center for Biotechnology Information, U.S. National Library of Medicine. Retrieved 2020-07-15.
  7. ^ "ARL6IP6 Gene". Gene Cards Human Gene Database.
  8. ^ Wichmann, Ignacio A.; Zavala, Kattina; Hoffmann, Federico G.; Vandewege, Michael W.; Corvalán, Alejandro H.; Amigo, Julio D.; Owen, Gareth I.; Opazo, Juan C. (2016). "Evolutionary history of the reprimo tumor suppressor gene family in vertebrates with a description of a new reprimo gene lineage". Gene. 591 (1): 245–254. doi:10.1016/j.gene.2016.07.036. PMID 27432065.