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Protein-coding gene in the species Homo sapiens
Apolipoprotein L3 is a protein that in humans is encoded by the APOL3 gene .[ 3] [ 4] [ 5]
This gene is a member of the apolipoprotein L gene family . The encoded protein is found in the cytoplasm , where it may affect the movement of lipids or allow the binding of lipids to organelles . In addition, expression of this gene is upregulated by tumor necrosis factor -alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta . Six transcript variants encoding three different isoforms have been found for this gene.[ 4]
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