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ANKRD15

From Wikipedia, the free encyclopedia

KANK1
Identifiers
AliasesKANK1, ANKRD15, CPSQ2, KANK, KN motif and ankyrin repeat domains 1
External IDsOMIM: 607704; MGI: 2147707; HomoloGene: 17706; GeneCards: KANK1; OMA:KANK1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_181404
NM_001348180

RefSeq (protein)

n/a

Location (UCSC)Chr 9: 0.47 – 0.75 MbChr 19: 25.21 – 25.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

KN motif and ankyrin repeat domain-containing protein 1 is a protein that in humans is encoded by the KANK1 gene.[5][6][7]

This gene encodes a protein containing four ankyrin repeat domains in its C-terminus. The suggested role for this protein is in tumorigenesis of renal cell carcinoma. Two alternatively spliced transcript variants encoding different isoforms have been identified.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000107104Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032702Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sarkar S, Roy BC, Hatano N, Aoyagi T, Gohji K, Kiyama R (Sep 2002). "A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma". J Biol Chem. 277 (39): 36585–91. doi:10.1074/jbc.M204244200. PMID 12133830.
  6. ^ Zhu Y, Kakinuma N, Wang Y, Kiyama R (Jan 2008). "Kank proteins: a new family of ankyrin-repeat domain-containing proteins". Biochim Biophys Acta. 1780 (2): 128–33. doi:10.1016/j.bbagen.2007.09.017. PMID 17996375.
  7. ^ a b "Entrez Gene: ANKRD15 ankyrin repeat domain 15".
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Further reading

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