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Protein-coding gene in the species Homo sapiens
ADAMTS-like protein 1 is a protein that in humans is encoded by the ADAMTSL1 gene .[ 5] [ 6] [ 7]
This gene encodes a secreted protein resembling members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the propeptide region and the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000178031 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066113 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Aug 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" . DNA Res . 5 (1): 31–9. doi :10.1093/dnares/5.1.31 PMID 9628581 . ^ Hirohata S, Wang LW, Miyagi M, Yan L, Seldin MF, Keene DR, Crabb JW, Apte SS (Apr 2002). "Punctin, a novel ADAMTS-like molecule, ADAMTSL-1, in extracellular matrix" . J Biol Chem . 277 (14): 12182–9. doi :10.1074/jbc.M109665200 PMID 11805097 . ^ a b "Entrez Gene: ADAMTSL1 ADAMTS-like 1" .
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