From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Golgi resident protein GCP60 is a protein that in humans is encoded by the ACBD3 gene .[ 5]
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. ACBD3 is involved in maintaining the Golgi structure by interacting with giantin, which affects the transport of protein.[ 6] [ 5]
ACBD3 has been shown to interact with GOLGB1 .[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000182827 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026499 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b "Entrez Gene: ACBD3 acyl-Coenzyme A binding domain containing 3" .^ "ACBD3 - Golgi resident protein GCP60 - Homo sapiens (Human) - ACBD3 gene & protein" .^ Sohda M, Misumi Y, Yamamoto A, Yano A, Nakamura N, Ikehara Y (November 2001). "Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin" . J. Biol. Chem . 276 (48): 45298–306. doi :10.1074/jbc.M108961200 PMID 11590181 .
Sohda M, Misumi Y, Yamamoto A, Yano A, Nakamura N, Ikehara Y (2002). "Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin" . J. Biol. Chem . 276 (48): 45298–306. doi :10.1074/jbc.M108961200 PMID 11590181 . Li H, Degenhardt B, Tobin D, Yao ZX, Tasken K, Papadopoulos V (2002). "Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein" . Mol. Endocrinol . 15 (12): 2211–28. doi :10.1210/mend.15.12.0736 PMID 11731621 . S2CID 27565320 . Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol . 21 (5): 566–9. doi :10.1038/nbt810 . PMID 12665801 . S2CID 23783563 . Liu J, Matyakhina L, Han Z, Sandrini F, Bei T, Stratakis CA, Papadopoulos V (2003). "Molecular cloning, chromosomal localization of human peripheral-type benzodiazepine receptor and PKA regulatory subunit type 1A (PRKAR1A)-associated protein PAP7, and studies in PRKAR1A mutant cells and tissues" . FASEB J . 17 (9): 1189–91. doi :10.1096/fj.02-1066fje PMID 12692076 . S2CID 19079882 . Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (2004). "Functional Proteomics Mapping of a Human Signaling Pathway" . Genome Res . 14 (7): 1324–32. doi :10.1101/gr.2334104 . PMC 442148 PMID 15231748 . Sbodio JI, Hicks SW, Simon D, Machamer CE (2006). "GCP60 preferentially interacts with a caspase-generated golgin-160 fragment" . J. Biol. Chem . 281 (38): 27924–31. doi :10.1074/jbc.M603276200 PMID 16870622 . Sbodio JI, Machamer CE (2007). "Identification of a redox-sensitive cysteine in GCP60 that regulates its interaction with golgin-160" . J. Biol. Chem . 282 (41): 29874–81. doi :10.1074/jbc.M705794200 PMID 17711851 .
