5-dehydro-4-deoxyglucarate dehydratase
Appearance
5-dehydro-4-deoxyglucarate dehydratase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.1.41 | ||||||||
CAS no. | 37290-77-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) catalyzes the chemical reaction
- 5-dehydro-4-deoxy-D-glucarate 2,5-dioxopentanoate + H2O + CO2
Enzyme class
[edit]This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating 2,5-dioxopentanoate-forming). Other names in common use include 5-keto-4-deoxy-glucarate dehydratase, deoxyketoglucarate dehydratase, D-4-deoxy-5-ketoglucarate hydro-lyase, and 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating). This enzyme participates in ascorbate and aldarate metabolism.
References
[edit]- Jeffcoat R, Hassall H, Dagley S (1969). "Purification and properties of D-4-deoxy-5-oxoglucarate hydro-lyase (decarboxylating)". Biochem. J. 115 (5): 977–83. PMC 1185240. PMID 4982840.