5-Methoxysalicylic acid

5-Methoxysalicylic acid
Names
	Preferred IUPAC name 2-Hydroxy-5-methoxybenzoic acid
	Other names 5-Methoxysalicylic acid; 6-Hydroxy-m-anisic acid; 5-Methoxy-2-hydroxybenzoic acid; m-Anisic acid; MSA
Identifiers
CAS Number	2612-02-4 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:89830;
ChemSpider	68296;
ECHA InfoCard	100.018.217
PubChem CID	75787;
UNII	6GAI2MTV5V ;
CompTox Dashboard (EPA)	DTXSID0062551 ;
	SMILES COC1=CC(=C(C=C1)O)C(=O)O;
Properties
Chemical formula	C8H8O4
Molar mass	168.148 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

5-Methoxysalicylic acid is a chemical compound. It is a component of castoreum, the exudate from the castor sacs of the mature beaver.^[1]

A mixture of 5-methoxysalicylic acid and spermine can be used as a matrix for oligonucleotides analysis in MALDI mass spectrometry.^[2]

It is an isomer of vanillic acid.

References

^ Müller-Schwarze, D.; Houlihan, Peter W. (1991). "Pheromonal activity of single castoreum constituents in beaver,Castor canadensis". Journal of Chemical Ecology. 17 (4): 715–734. Bibcode:1991JCEco..17..715M. doi:10.1007/BF00994195. PMID 24258917. S2CID 29937875.
^ Distler, AM; Allison, J (2001). "5-Methoxysalicylic acid and spermine: A new matrix for the matrix-assisted laser desorption/ionization mass spectrometry analysis of oligonucleotides". Journal of the American Society for Mass Spectrometry. 12 (4): 456–62. Bibcode:2001JASMS..12..456D. doi:10.1016/S1044-0305(01)00212-4. PMID 11322192. S2CID 18280663.

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