4'-Fluoro-4-methylaminorex

4'-Fluoro-4-methylaminorex
Identifiers
	IUPAC name 4-methyl-5-(4-fluorophenyl)-4,5-dihydro-1,3-oxazol-2-amine;
CAS Number	1364933-64-1 ;
PubChem CID	134080816;
ChemSpider	78231362;
UNII	QMW9X4B373;
CompTox Dashboard (EPA)	DTXSID501336900 ;
Chemical and physical data
Formula	C10H11FN2O
Molar mass	194.209 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc1ccc(cc1)C1OC(N)=NC1C;
	InChI InChI=1S/C10H11FN2O/c1-6-9(14-10(12)13-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H2,12,13); Key:UYKYWISHPDEDRQ-UHFFFAOYSA-N;

4'-Fluoro-4-methylaminorex (4F-MAR, 4-FPO) is a recreational designer drug from the substituted aminorex family, with stimulant effects. It was first detected in Slovenia in 2018.^[1]^[2]^[3] It was made illegal in Italy in March 2020.^[4]

References

^ Fabregat-Safont D, Carbón X, Ventura M, Fornís I, Hernández F, Ibáñez M (June 2019). "Characterization of a recently detected halogenated aminorex derivative: para-fluoro-4-methylaminorex (4'F-4-MAR)". Scientific Reports. 9 (1): 8314. Bibcode:2019NatSR...9.8314F. doi:10.1038/s41598-019-44830-y. PMC 6549166. PMID 31165778.
^ Maier J, Mayer FP, Brandt SD, Sitte HH (October 2018). "DARK Classics in Chemical Neuroscience: Aminorex Analogues". ACS Chemical Neuroscience. 9 (10): 2484–2502. doi:10.1021/acschemneuro.8b00415. PMC 6287711. PMID 30269490.
^ Seibert E, Kunert O, Pferschy-Wenzig EM, Schmid MG (September 2022). "Characterization of Three Novel 4-Methylaminorex Derivatives Applied as Designer Drugs". Molecules (Basel, Switzerland). 27 (18): 5770. doi:10.3390/molecules27185770. PMC 9503756. PMID 36144500.
^ "DECRETO 13 marzo 2020. Aggiornamento delle tabelle contenenti l'indicazione delle sostanze stupefacenti e psicotrope" [Update of the tables containing the indication of narcotic and psychotropic substances]. Official Gazette (in Italian). The Republic of Italy. 13 March 2020. di cui al decreto del Presidente della Repubblica 9 ottobre 1990, n. 309 e successive modificazioni ed integrazioni. Inserimento nella tabella I e nella tabella IV di nuove sostanze psicoattive. (20A01820) (GU Serie Generale n.85 del 30-03-2020) [as per the decree of the President of the Republic October 9, 1990, n. 309 and subsequent amendments and additions. Inclusion in Table I and Table IV of new psychoactive substances. (20A01820) (GU General Series n.85 of 30-03-2020)]

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[pmid31165778-1] Fabregat-Safont D, Carbón X, Ventura M, Fornís I, Hernández F, Ibáñez M (June 2019). "Characterization of a recently detected halogenated aminorex derivative: para-fluoro-4-methylaminorex (4'F-4-MAR)". Scientific Reports. 9 (1): 8314. Bibcode:2019NatSR...9.8314F. doi:10.1038/s41598-019-44830-y. PMC 6549166. PMID 31165778.

[pmid30269490-2] Maier J, Mayer FP, Brandt SD, Sitte HH (October 2018). "DARK Classics in Chemical Neuroscience: Aminorex Analogues". ACS Chemical Neuroscience. 9 (10): 2484–2502. doi:10.1021/acschemneuro.8b00415. PMC 6287711. PMID 30269490.

[pmid36144500-3] Seibert E, Kunert O, Pferschy-Wenzig EM, Schmid MG (September 2022). "Characterization of Three Novel 4-Methylaminorex Derivatives Applied as Designer Drugs". Molecules (Basel, Switzerland). 27 (18): 5770. doi:10.3390/molecules27185770. PMC 9503756. PMID 36144500.

[4] "DECRETO 13 marzo 2020. Aggiornamento delle tabelle contenenti l'indicazione delle sostanze stupefacenti e psicotrope" [Update of the tables containing the indication of narcotic and psychotropic substances]. Official Gazette (in Italian). The Republic of Italy. 13 March 2020. di cui al decreto del Presidente della Repubblica 9 ottobre 1990, n. 309 e successive modificazioni ed integrazioni. Inserimento nella tabella I e nella tabella IV di nuove sostanze psicoattive. (20A01820) (GU Serie Generale n.85 del 30-03-2020) [as per the decree of the President of the Republic October 9, 1990, n. 309 and subsequent amendments and additions. Inclusion in Table I and Table IV of new psychoactive substances. (20A01820) (GU General Series n.85 of 30-03-2020)]

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See also

References