3-hydroxypropionate dehydrogenase
| 3-hydroxypropionate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.59 | ||||||||
| CAS no. | 9028-59-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-hydroxypropionate dehydrogenase (EC 1.1.1.59) is an enzyme that catalyzes the chemical reaction
- 3-hydroxypropanoate + NAD+ 3-oxopropanoate + NADH + H+
Thus, the two substrates of this enzyme are 3-hydroxypropanoate and NAD+, whereas its 3 products are 3-oxopropanoate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-hydroxypropanoate:NAD+ oxidoreductase. This enzyme participates in beta-alanine metabolism and propanoate metabolism.
References
[edit]- Den H, Robinson WG, Coon MJ (1959). "Enzymatic conversion of beta-hydroxypropionate to malonic semialdehyde". J. Biol. Chem. 234 (7): 1666–1671. PMID 13672942.
