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3-cyanoalanine hydratase

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3-cyanoalanine hydratase
Identifiers
EC no.4.2.1.65
CAS no.37259-64-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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Gene OntologyAmiGO / QuickGO
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The enzyme 3-cyanoalanine hydratase (EC 4.2.1.65) catalyzes the chemical reaction

L-asparagine 3-cyanoalanine + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is L-asparagine hydro-lyase (3-cyanoalanine-forming). Other names in common use include β-cyanoalanine hydrolase, β-cyanoalanine hydratase, β-CNAla hydrolase, β-CNA nitrilase, and L-asparagine hydro-lyase. This enzyme participates in cyanoamino acid metabolism.

References

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  • Castric PA, Farnden KJ, Conn EE (September 1972). "Cyanide metabolism in higher plants. V. The formation of asparagine from -cyanoalanine". Archives of Biochemistry and Biophysics. 152 (1): 62–9. doi:10.1016/0003-9861(72)90193-2. PMID 4627358.