The 2022 Weber State Wildcats football team represented Weber State University as a member of the Big Sky Conference during the 2022 NCAA Division I FCS football season. The Wildcats were led by ninth-year head coach Jay Hill and played their games at Stewart Stadium in Ogden, Utah. The Wildcats began the regular season ranked number 20 in the FCS rankings. On September 10, the Wildcats defeated the Utah State Aggies, their first win against the Aggies since 1978, and their first win against an FBS opponent since their victory against Nevada in 1993. The Wildcats finished the regular season with a record of 9–2, good enough to qualify for the NCAA Division I FCS Playoffs, their fifth appearance under Jay Hill. The Wildcats defeated North Dakota in the opening round, but were defeated by Montana State the following round. After the season, head coach Jay Hill announced he would step down as Weber State head coach to accept the Defensive Coordinator position at BYU. Offensive coordinator Mickey Mental was announced as Hill's successor.