2,5-dioxopiperazine hydrolase
Appearance
2,5-dioxopiperazine hydrolase | |||||||||
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Identifiers | |||||||||
EC no. | 3.5.2.13 | ||||||||
CAS no. | 97599-45-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 2,5-dioxopiperazine hydrolase (EC 3.5.2.13) is an enzyme that catalyzes the chemical reaction
- 2,5-dioxopiperazine + H2O glycylglycine
Thus, the two substrates of this enzyme are 2,5-dioxopiperazine and H2O, whereas its product is glycylglycine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 2,5-dioxopiperazine amidohydrolase. Other names in common use include cyclo(Gly-Gly) hydrolase, and cyclo(glycylglycine) hydrolase.
References
[edit]- Suzuki Y, Uchida K (1985). "Multiple forms of alpha-glycosidase from pig duodenum". Agric. Biol. Chem. 49 (6): 1573–1581. doi:10.1271/bbb1961.49.1573.