2,4,6-Trichloroaniline
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| Names | |||
|---|---|---|---|
| Preferred IUPAC name
2,4,6-Trichloroaniline | |||
| Identifiers | |||
3D model (JSmol)
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| ChEMBL | |||
| ChemSpider | |||
| ECHA InfoCard | 100.010.200 | ||
| EC Number |
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PubChem CID
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| UNII | |||
| UN number | 2811 | ||
CompTox Dashboard (EPA)
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| Properties | |||
| C6H4Cl3N | |||
| Molar mass | 196.46 g·mol−1 | ||
| Appearance | Long needles or fine, light purple fibers [1] | ||
| Melting point | 78.5 °C (173.3 °F; 351.6 K) | ||
| Boiling point | 262 °C (504 °F; 535 K) | ||
| 40 mg/L | |||
| Solubility | chloroform, ether, ethanol [2] | ||
| log P | 3.69 | ||
| Vapor pressure | 1.47×10−7 mmHg | ||
| Acidity (pKa) | 0.07 (for the conjugate acid) | ||
| Basicity (pKb) | 13.93 | ||
| Hazards | |||
| Occupational safety and health (OHS/OSH): | |||
Main hazards
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Harmful, corrosive, toxic | ||
| GHS labelling: | |||
   
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| Danger | |||
| H301, H311, H317, H331, H373, H410, H411 | |||
| P260, P261, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P311, P312, P314, P321, P322, P330, P333+P313, P361, P363, P391, P403+P233, P405, P501 | |||
| NFPA 704 (fire diamond) | |||
| Flash point | 110 °C (230 °F; 383 K) | ||
| Decomposes | |||
| Lethal dose or concentration (LD, LC): | |||
LD50 (median dose)
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2400 mg/kg (rat, oral) | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2,4,6-Trichloroaniline is a chemical compound with a formula of C6H4Cl3N. It is useful as an intermediate in chemical reactions.[2]
Preparation
[edit]2,4,6-Trichloroaniline can be prepared by reaction of dry aniline with chlorine gas while in an anhydrous solution of carbon tetrachloride. 2,4,6-Trichloroaniline precipitates from solution as a white solid. In the presence of water in the solution the white material will be contaminated with aniline black.[3]
Safety
[edit]Occupational exposure to 2,4,6-trichloroaniline may occur through inhalation and dermal contact with this compound at workplaces where 2,4,6-trichloroaniline is produced or used (SRC). The general population may be exposed to 2,4,6-trichloroaniline via drinking water and dermal contact with this compound in dyestuffs, pigments, and pesticides containing 2,4,6-trichloroaniline.[4] 2,4,6-trichloroaniline can be toxic when inhaled or ingested orally. The lethal dose is 2400 mg/kg for a rat.[1]
Upon heating, 2,4,6-trichloroaniline will not undergo combustion, but may release hydrogen chloride, nitrogen oxides or carbon monoxide.[1]
References
[edit]- ^ a b c "2,4,6-Trichloroaniline(634-93-5) MSDS Melting Point Boiling Point Density Storage Transport". www.chemicalbook.com. Retrieved 2019-03-14.
- ^ a b Pubchem. "2,4,6-Trichloroaniline". pubchem.ncbi.nlm.nih.gov. Retrieved 2019-03-14.
- ^ "Synthesis of 2,4,6-trichloroaniline". PrepChem.com. 2016-08-15. Retrieved 2019-03-13.
- ^ "TOXNET". toxnet.nlm.nih.gov. Archived from the original on 2019-03-31. Retrieved 2019-03-14.
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