16S rRNA (cytosine967-C5)-methyltransferase
| 16S rRNA (cytosine967-C5)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.176 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
16S rRNA (cytosine967-C5)-methyltransferase (EC 2.1.1.176, rsmB (gene), fmu (gene), 16S rRNA m5C967 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (cytosine967-C5)-methyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + cytosine967 in 16S rRNA S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA
The enzyme specifically methylates cytosine967 at C5 in 16S rRNA.
References
[edit]- ^ Tscherne JS, Nurse K, Popienick P, Michel H, Sochacki M, Ofengand J (February 1999). "Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli". Biochemistry. 38 (6): 1884–92. doi:10.1021/bi981880l. PMID 10026269.
- ^ Gu XR, Gustafsson C, Ku J, Yu M, Santi DV (March 1999). "Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli". Biochemistry. 38 (13): 4053–7. doi:10.1021/bi982364y. PMID 10194318.
- ^ Foster PG, Nunes CR, Greene P, Moustakas D, Stroud RM (December 2003). "The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate". Structure. 11 (12): 1609–20. doi:10.1016/j.str.2003.10.014. PMID 14656444.
External links
[edit]- 16S+rRNA+(cytosine967-C5)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
