(S)-N-acetyl-1-phenylethylamine hydrolase
Appearance
(S)-N-acetyl-1-phenylethylamine hydrolase | |||||||||
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Identifiers | |||||||||
EC no. | 3.5.1.85 | ||||||||
CAS no. | 192230-94-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a (S)-N-acetyl-1-phenylethylamine hydrolase (EC 3.5.1.85) is an enzyme that catalyzes the chemical reaction
- N-acetylphenylethylamine + H2O phenethylamine + acetate
Thus, the two substrates of this enzyme are N-acetylphenylethylamine and H2O, whereas its two products are phenethylamine and acetate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is (S)-N-acetylphenylethylamine:H2O hydrolase. At least one compound, phenylmethanesulfonylfluoride is known to inhibit this enzyme.
References
[edit]- Brunella A, Graf M, Kittelmann M, Lauma K, Ghisalba O (1997). "Production, purification, and characterization of a highly enantioselective (S)-N-acetyl-1-phenylethyl amidohydrolase from Rhodococcus". Appl. Microbiol. Biotechnol. 47 (5): 515–520. doi:10.1007/s002530050965.