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(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase

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(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
Identifiers
EC no.4.1.3.35
CAS no.71343-09-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PubMedarticles
NCBIproteins

The enzyme (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase (EC 4.1.3.35) catalyzes the chemical reaction

(1-hydroxycyclohexan-1-yl)acetyl-CoA acetyl-CoA + cyclohexanone

Hence, this enzyme has one substrate, (1-hydroxycyclohexan-1-yl)acetyl-CoA, and two products, acetyl-CoA and cyclohexanone.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming). This enzyme is also called (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase.

References

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  • Ougham HJ, Trudgill PW (June 1982). "Metabolism of cyclohexaneacetic acid and cyclohexanebutyric acid by Arthrobacter sp. strain CA1". Journal of Bacteriology. 150 (3): 1172–82. PMC 216338. PMID 7076617.