Wd repeat domain 76

WDR76
Identifiers
Aliases	WDR76, CDW14, WD repeat domain 76
External IDs	MGI: 1926186; HomoloGene: 38573; GeneCards: WDR76; OMA:WDR76 - orthologs
Gene location (Human) Chr. Chromosome 15 (human) Band 15q15.3 Start 43,826,980 bp End 43,868,412 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 E5 Start 121,337,204 bp End 121,375,341 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte ganglionic eminence ventricular zone secondary oocyte endothelial cell testicle gonad Achilles tendon bone marrow cells stromal cell of endometrium Top expressed in zygote secondary oocyte superior cervical ganglion primary oocyte tail of embryo thymus genital tubercle ventricular zone epiblast hand More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein binding enzyme binding Cellular component nucleus heterochromatin site of DNA damage Biological process cellular response to DNA damage stimulus regulation of DNA damage checkpoint Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79968 241627 Ensembl ENSG00000092470 ENSMUSG00000027242 UniProt Q9H967 A6PWY4 RefSeq (mRNA) NM_001167941 NM_024908 NM_001290986 NM_001290987 NM_030234 NM_001369185 RefSeq (protein) NP_001161413 NP_079184 NP_001277915 NP_001277916 NP_084510 NP_001356114 Location (UCSC) Chr 15: 43.83 – 43.87 Mb Chr 2: 121.34 – 121.38 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

WD repeat domain 76 is a protein that in humans is encoded by the WDR76 gene.

Further reading

• Fleischmann C, Bevan S, Neil JC, Terry A, Houlston RS (June 2003). "Mutations in the candidate tumour suppressor gene FLJ12973 on chromosome 15q15 are rare in colorectal cancer". Cancer Lett. 196 (1): 65–7. doi:10.1016/s0304-3835(03)00160-5. PMID 12860291.
• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
• Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.