Total analysis system

The term total analysis system (TAS) describes a device that combines and automates all necessary steps for the chemical analysis of a sample (e.g., sampling, sample transport, filtration, dilution, chemical reactions, separation, and detection).^[1]^[2] Most current total analysis systems are "micro" total analysis systems which utilize the principles of microfluidics.^[3]^[4]

Total analysis systems are designed to shrink the processes carried out in a laboratory to a chip-sized lab-on-a-chip. Due to this, it can be more cost-effective to carry out complex tests when considering chip technologies, sample sizes, and analysis time. Total analysis systems can also reduce the exposure of toxic chemicals for lab personnel. This technology can also be used in point-of-care testing or point-of-use diagnostics, which do not require skilled technicians.^[3]

References

^ Justino, Celine I. L.; Rocha-Santos, Teresa A. P.; Duarte, Armando C. (2018-01-01), Hussain, Chaudhery Mustansar (ed.), "Chapter 14 - Nanomaterials in Lab-on-Chip Chromatography", Nanomaterials in Chromatography, Elsevier, pp. 387–400, doi:10.1016/b978-0-12-812792-6.00014-5, ISBN 978-0-12-812792-6, retrieved 2024-05-31
^ Cagliero, Cecilia; Sgorbini, Barbara; Cordero, Chiara; Liberto, Erica; Rubiolo, Patrizia; Bicchi, Carlo (2021-01-01), Poole, Colin F. (ed.), "Chapter 23 - Separation of stereoisomers by gas chromatography", Gas Chromatography (Second Edition), Handbooks in Separation Science, Amsterdam: Elsevier, pp. 581–614, doi:10.1016/b978-0-12-820675-1.00015-0, ISBN 978-0-12-820675-1, retrieved 2024-05-31
^ ^a ^b Reyes, Darwin R.; Iossifidis, Dimitri; Auroux, Pierre-Alain; Manz, Andreas (2002-06-01). "Micro Total Analysis Systems. 1. Introduction, Theory, and Technology". Analytical Chemistry. 74 (12): 2623–2636. doi:10.1021/ac0202435. ISSN 0003-2700. PMID 12090653.
^ Catarino, S.; Lima, R.; Minas, G. (2017-01-01), Rodrigues, Lígia; Mota, Manuel (eds.), "12 - Smart devices: Lab-on-a-chip", Bioinspired Materials for Medical Applications, Woodhead Publishing, pp. 331–369, doi:10.1016/b978-0-08-100741-9.00012-7, ISBN 978-0-08-100741-9, retrieved 2024-05-31

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[1] Justino, Celine I. L.; Rocha-Santos, Teresa A. P.; Duarte, Armando C. (2018-01-01), Hussain, Chaudhery Mustansar (ed.), "Chapter 14 - Nanomaterials in Lab-on-Chip Chromatography", Nanomaterials in Chromatography, Elsevier, pp. 387–400, doi:10.1016/b978-0-12-812792-6.00014-5, ISBN 978-0-12-812792-6, retrieved 2024-05-31

[2] Cagliero, Cecilia; Sgorbini, Barbara; Cordero, Chiara; Liberto, Erica; Rubiolo, Patrizia; Bicchi, Carlo (2021-01-01), Poole, Colin F. (ed.), "Chapter 23 - Separation of stereoisomers by gas chromatography", Gas Chromatography (Second Edition), Handbooks in Separation Science, Amsterdam: Elsevier, pp. 581–614, doi:10.1016/b978-0-12-820675-1.00015-0, ISBN 978-0-12-820675-1, retrieved 2024-05-31

[:0-3] Reyes, Darwin R.; Iossifidis, Dimitri; Auroux, Pierre-Alain; Manz, Andreas (2002-06-01). "Micro Total Analysis Systems. 1. Introduction, Theory, and Technology". Analytical Chemistry. 74 (12): 2623–2636. doi:10.1021/ac0202435. ISSN 0003-2700. PMID 12090653.

[4] Catarino, S.; Lima, R.; Minas, G. (2017-01-01), Rodrigues, Lígia; Mota, Manuel (eds.), "12 - Smart devices: Lab-on-a-chip", Bioinspired Materials for Medical Applications, Woodhead Publishing, pp. 331–369, doi:10.1016/b978-0-08-100741-9.00012-7, ISBN 978-0-08-100741-9, retrieved 2024-05-31

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References