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Edward Tuddenham

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Edward G. D. Tuddenham
Born1944
CitizenshipBritish
Alma materUniversity of London
Known forPurification and cloning of factor VIII, gene therapy for haemophilia
AwardsFellowship of the Academy of Medical Sciences, Barry Firkin Award 2006, Henri Chaigneau Award 2012
Scientific career
Fieldshaematology
InstitutionsUniversity College London, Royal Free Hospital

Edward G. D. Tuddenham is a British haematologist who has authored over 200 papers in the field. He gained his Bachelor of Medicine, Bachelor of Surgery at the University of London in 1968 and his Membership of the Royal College of Physicians in 1975. Up until 2005 was head of the Haemostasis and Thrombosis Research (Medical Research Council) Group at Imperial College. Professor Tuddenham is a pioneer in the field of haemophilia and was responsible, along with Frances Rotblat, for the purification and cloning of the factor VIII gene, which led to the highly effective and safe treatments available to haemophilia sufferers today. In more recent years, he has been actively involved in developing gene therapy for haemophilia. The first successful use of gene transfer to convert severe to mild haemophilia B was reported by his group in December 2011.He retired from Directorship of the Katharine Dormandy Centre in July 2011 and is now Emeritus Professor of Haemophilia at University College London. He continues to work in the Haemophilia Centre at the Royal Free Hospital on gene therapy clinical trials, with the goal of curing all forms of haemophilia.

References

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  • Mark Smith. "2006 Barry Firkin Orator Professor Ted Tuddenham – The FVXIII Story" (PDF). Archived from the original (PDF) on 29 August 2007.
  • E. G. D. Tuddenham (March 2003). "In search of the eighth factor: a personal reminiscence". Journal of Thrombosis and Haemostasis. 1 (3): 403–409. doi:10.1046/j.1538-7836.2003.00163.x. PMID 12871437. S2CID 40301087.
  • Christie, D.A. & Tansey, E.M. (editors) (February 1998). "Haemophilia: Recent History of Clinical Management" (PDF). {{cite web}}: |author= has generic name (help)CS1 maint: multiple names: authors list (link)
  • Wade,Nicholas (10 December 2011). "NY Times: Treatment for Blood Disease Is Gene Therapy Landmark". The New York Times.
  • "PubMed results for Tuddenham EG". 27 June 2012.
  • "Frances Rotblat obituary". The Times. 12 June 2021. Retrieved 12 June 2021.