Talk:Prepulse inhibition

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Cut a phrase from previous edit

Maybe later I'll find this review and put it to the text:

In addition to animal models, PPI has also been explored in humans, supporting the validity of these procedures in studying schizophrenia (for review, see Braff et al. 2002).

CopperKettle 16:01, 11 May 2007 (UTC)[reply]

What is necessary to improve this article

More information on PPI disruption in numerous diseases;
An outline of brain circuitry underlying the startle response and its inhibition and computer models of such circuits;
More images: screenshots of registering software, printouts, photos of people tested, mice tested, other species tested;
Examples of startle sounds also could be added;
Would be great if the article was reviewed by a specialist of the field, for example, Neal Swerdlow;
Table of influence of different chemical compounds on PPI in different species, with different reactions across species highlighted;

CopperKettle 18:12, 11 May 2007 (UTC)[reply]

PPI and antipsychotics

There are no references supporting that antipsychotics improves PPI in schizophrenic. As far as I can see Swerdlow 2007 does not have information about this. Also references would be needed for schizophrenics that never have been recieving antipsychotics since the impaired PPI may be a temporary condition (like in panic disorder) or an impairment from antipsychotics. --Nopedia (talk) 02:07, 21 February 2010 (UTC)[reply]

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