Talk:NeuroAiD

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Requested move

The following discussion is an archived discussion of a requested move. Please do not modify it. Subsequent comments should be made in a new section on the talk page. No further edits should be made to this section.

The result of the move request was: page moved. Vegaswikian (talk) 02:37, 30 April 2010 (UTC)[reply]

Danqi Jiaonang → Neuroaid — Relisting. Vegaswikian (talk) 22:05, 20 April 2010 (UTC)[reply]

Danqi Jiaonang is a traditional chinese medecine which is currently used in China. Neuroaid is a stroke treatment which takes its origines in Danqi Jiaonang but which is more than simply Danqi Jiaonang.Furthermore All clinical trials stated in the page were made on neuroaid and not on Danqi Jiaonang. Argenlieu (talk) 04:27, 12 April 2010 (UTC)[reply]

Support Rubberstamp endorse since this has been unopposed and open for more than 2 weeks. --Cybercobra (talk) 07:21, 29 April 2010 (UTC)[reply]

The above discussion is preserved as an archive of a requested move. Please do not modify it. Subsequent comments should be made in a new section on this talk page. No further edits should be made to this section.

WP:MED

FYI, I have posted a query about this article on the WP:MED Talk page. Alexbrn ^{talk|contribs|COI} 07:37, 14 May 2013 (UTC)[reply]

Thanks. The article needs secondary sources like doi:10.1016/j.drudis.2012.02.011. I don't have access to it though. Biosthmors (talk) 23:30, 16 May 2013 (UTC)[reply]

I do. Since text for neuroaid is not long I will post it here under fair use conditions so we can all see it. We should eliminate it as soon as possible. Great job finding it.--Garrondo (talk) 06:43, 17 May 2013 (UTC)[reply]

From doi:10.1016/j.drudis.2012.02.011: NeuroAiD™ (MLC601 and MLC901), a traditional Chinese medicine has been used in China in patients after stroke as drugs to facilitate recovery after stroke since 2001. These agents combine nine herbal and five animal components. In vitro and in vivo results showed that NeuroAiD made cells more resistant against glutamate aggression, increased neurite outgrowth and connectivity and reduced infarct volume [41]. In a rodent model with focal ischemia an improved survival, brain protection and decreased functional deficits were demonstrated. MLC901 also prevented neuronal death in an in vitro model and induced neurogenesis in rodent and human cells [41]. Chen et al. analyzed the improvement of neurological recovery after stroke 2009 in clinical trials [42]. A recent study showed that MLC901 can also improve functional recovery of rats after global ischemia, because it was found to have an important role in neuroprotection [3]. Overall, NeuroAID, as it has already been effective in a cohort of Chinese patients with stroke, seems to represent an interesting agent in stroke treatment.

Refs:

3-H. Quintard et al. MLC901, a Traditional Chinese Medicine protects the brain against global ischemia. Neuropharmacology, 61 (2011), pp. 622–631
41-C. Heurteaux et al.Neuroprotective and neuroproliferative activities of NeuroAid (MLC601, MLC901), a Chinese medicine, in vitro and in vivo. Neuropharmacology, 58 (2010), pp. 987–1001
42-C. Chen et al.Danqi Piantang Jiaonang (DJ), a traditional Chinese medicine, in poststroke recovery.Stroke, 40 (2009), pp. 859–863

Reverted

I reverted a recent edit, which appeared promotional, as mentioned here. Biosthmors (talk) 08:04, 15 August 2013 (UTC)[reply]

Alzheimers

I've removed this sentence:

It has also shown effectiveness as a complementary treatment for other brain injuries and Alzheimer's disease.^[1]

^ Chen CL, Sharma PR, Tan BY, Low C, Venketasubramanian N (2019). "The Alzheimer's disease THErapy with NEuroaid (ATHENE) study protocol: Assessing the safety and efficacy of Neuroaid II (MLC901) in patients with mild-to-moderate Alzheimer's disease stable on cholinesterase inhibitors or memantine-A randomized, double-blind, placebo-controlled trial". Alzheimer's & Dementia. 5: 38–45. doi:10.1016/j.trci.2018.12.001. PMC 6352850. PMID 30723778.

I have removed this sentence because the source is about a clinical trial that they plan to do sometime in the future. It is not a clinical trial that already happened. There is no data here and no conclusion that it is actually effective. (Also, that'd be a Adjuvant therapy, not necessarily a Complementary therapy.) WhatamIdoing (talk) 17:16, 9 April 2022 (UTC)[reply]

Short description

I modified the short description (diff) so that it now reads: "Supposed post-stroke ameliorative supplement". By "supposed" (pronunciation: \ sə-ˈpō-zəd \), I mean "erroneously imputed or ascribed".^[1]. If that meaning does not seem clear, please edit for clarity. (It's clear to me, but not everyone is a word geek . ;^) Mark D Worthen PsyD (talk) [he/him] 17:33, 10 April 2022 (UTC)[reply]

References

^ Merriam-Webster's Unabridged Dictionary, s.v. “supposed,” accessed April 10, 2022, https://unabridged.merriam-webster.com/unabridged/supposed

[pmid30723778-1] Chen CL, Sharma PR, Tan BY, Low C, Venketasubramanian N (2019). "The Alzheimer's disease THErapy with NEuroaid (ATHENE) study protocol: Assessing the safety and efficacy of Neuroaid II (MLC901) in patients with mild-to-moderate Alzheimer's disease stable on cholinesterase inhibitors or memantine-A randomized, double-blind, placebo-controlled trial". Alzheimer's & Dementia. 5: 38–45. doi:10.1016/j.trci.2018.12.001. PMC 6352850. PMID 30723778.

[2] Merriam-Webster's Unabridged Dictionary, s.v. “supposed,” accessed April 10, 2022, https://unabridged.merriam-webster.com/unabridged/supposed

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