Talk:Choanal atresia

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Is this a human only ailment...

...or is this an affliction in some, or all, mammals or otherwise all species? LessHeard vanU 15:33, 16 June 2007 (UTC)[reply]

Does "risk factors" merit inclusion of other epidemiological studies? These are not demonstrated causes, but potential links and may create undue confusions or fears about this. — Preceding unsigned comment added by 198.228.201.146 (talk) 16:32, 2 October 2012 (UTC)[reply]

It seems like there are a few "suspected" possible risk factors for Choanal atresia but no demonstrated or known causes, among which are any "endocrine disrupting" chemicals (which include a very wide range of natural and synthetic compounds that range from coffee to vitamins). These compounds are correlated/linked via epidemiological assessments (which do not indicate cause) to a range of birth defect-related conditions, not just Choanal atresia. Also, the reference to a recent study linking endocrine disrupting chemicals (and then specifically linking pesticides) needs to be cited as no such study is evident in the literature. If such a study exists, the type (meta, epidemiological, etc...) should be similarly cited as no defined causes - other than one citation linking the use of an alternative/herbal health therapy^[1] - are accepted in the literature. There are several, including this most recent herbicide study, epidemiological assessments for Choanal atresia. To avoid spreading untoward fears and potentially adverse health impacting behaviors, it should be made clear (as is typically done in all such epidemiological papers) that this is not an indication of cause - only an association which merits additional review and clinical research. For example, women SHOULD NOT avoid prenatal supplements when prescribed by their doctors (most of which include vitamin B12 and zinc), just because there was a 230-270 fold increase in incidents of Choanal atresia associated with use of these two endocrine disrupting compounds in a 2010 epidemiological study. As such, do epidemiological associations even belong in a section on "risk factors" for this or other diseases?

References

^ Choanal atresia: an unusual serious complication of complementary and alternative medical treatment, by Tseng CC, Tsai TL, Chen KT, Lin CZ., Arch Otolaryngol Head Neck Surg. 2003 Apr;129(4):475-7.

[1] Choanal atresia: an unusual serious complication of complementary and alternative medical treatment, by Tseng CC, Tsai TL, Chen KT, Lin CZ., Arch Otolaryngol Head Neck Surg. 2003 Apr;129(4):475-7.

[1]