Talk:C-C chemokine receptor type 7

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There is a reference made to ECL. Shouldn't it be ELC? —Preceding unsigned comment added by 129.64.176.241 (talk) 21:28, 10 December 2007 (UTC)[reply]

Taken straight from Entrez Gene ([1])... But typos at NCBI aren't unheard of -- if you're sure it should be ELC, then make the change (preferably while adding some explanatory text and ideally a reference or two...) Cheers, AndrewGNF (talk) 21:39, 10 December 2007 (UTC)[reply]

HUGO [2] give "ELC" (EBI1 ligand chemokine) as alias for CCL19. Even if ECL is used sometimes [3], ELC is far more common. --Banus (talk) 23:55, 11 December 2007 (UTC)[reply]

Assessment comment

The comment(s) below were originally left at Talk:C-C chemokine receptor type 7/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

you wrote :" It has been shown to control the migration of memory T cells to inflamed tissues"

CCR7 is involved into homing cells to the lymph nodes and not to leave them. for example central memory cells that express CCR7 can be attracted to the Lymph nodes, but effector memory cells lack CCR7 and than can stay in the tissues!

see Janeway's Immnulogy seventh edition, Kenneth Murphy and Paul Travers page 449 section 10-17 another example are the lymphoid tissue inducer cells (LTi), that express CCR7, which promote their homing to sites of future lymphoid organ developpment. see: Ectopic lymphoid tissues and local immunity Damian M. Carragher, Javier Rangel-Moreno, and Troy D. Randall

From the Trudeau Institute, 154 Algonquin Avenue, Saranac Lake, NY 12983

Last edited at 13:09, 26 May 2009 (UTC). Substituted at 10:37, 29 April 2016 (UTC)

Page Assesment (Reference [8])

It is stated that:

"Activation of Dendritic cells in peripheral tissues induces CCR7 expression on the cell's surface, which recognize CCL19 and CCL21 produced in the Lymph node and increases dendritic cell expression of co-stimulation molecules (B7), and MHC class I or MHC class II.[8]"

Going to references and reading the article, reference [8] has no mention of B7 or MHC protein complexes, aside from designating mature dendritic cells as HLA-DR high cells. Instead, it mentions that ligation of CCR7 is for chemotactic purposes. I could not find a publication on pubmed making such claims. Can someone provide a proper source for that statement, or change the page to accurately report the results of the article?

141.151.23.25 (talk) 00:38, 7 June 2020 (UTC)[reply]