Talk:Anti-interleukin-6

Move discussion in progress

There is a move discussion in progress on Talk:Interferon-γ Receptor-1 and 2 Mutations which affects this page. Please participate on that page and not in this talk page section. Thank you. —RMCD bot 08:30, 15 May 2013 (UTC)

Consensus was to leave the 2nd hyphen in the title of this article. - Rod57 (talk) 11:58, 15 August 2014 (UTC)

IL-6 may be anti-inflammatory

Dr. Bente Klarlund Pedersen has show IL-6 to be an anti-inflammatory agent when produced through muscular contraction in exercise. This would seem to call anti-IL-6 therapies into question. "IL-6 is the myokine prototype (Fig. 7). The systemic level of IL-6 increases markedly with exercise and skeletal muscle is the main source of origin. Muscle contractions lead to the production and release into the circulation of IL-6, which appears to have numerous biological effects, including effects on glucose and fat metabolism. In addition, IL-6 has a role in myogenesis and mediates anti-inflammatory effects." Muscle as a secretory organ. Pedersen BK Compr Physiol 2013; 3(3): 1337-62 http://www.inflammation-metabolism.dk/index.php?pageid=21&pmid=23897689 Laurence R. Hunt, Kenora, Canada 17:10, 6 October 2013 (UTC) — Preceding unsigned comment added by Lhuntkenora (talk • contribs)

All mention of possible beneficial effects of exercise-induced IL-6 seems to belong in the IL-6 article - not in this summary of anti-IL-6 drugs/therapies. - Rod57 (talk) 21:03, 31 October 2015 (UTC)

External links modified

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Could group those that act on IL-6 and those that act on the main receptor

Since the effects and side-effects are expected to be different, we could group those that act on IL-6 separate from those that act on the main receptor ? - Rod57 (talk) 14:35, 3 February 2017 (UTC)