Talk:14-3-3 protein

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Citation for

"Eukaryotes can tolerate the loss of a single 14-3-3 gene if multiple genes are expressed, however deletion of all 14-3-3s (as experimentally determined in yeast) results in death.[citation needed]" see PMID 7744048

Reference

Reference for "Phosphorylation of Cdc25C by CDS1 and CHK1 creates a binding site for the 14-3-3 family of phosphoserine binding proteins. Binding of 14-3-3 has little effect on Cdc25C activity, and it is believed that 14-3-3 regulates Cdc25C by sequestering it to the cytoplasm, thereby preventing the interactions with CycB-Cdk1 that are localized to the nucleus at the G2/M transition." can be found at Pubmed:18059525. Great article by the way. —Preceding unsigned comment added by 130.225.14.187 (talk) 09:47, 16 August 2010 (UTC)[reply]

Done

Assessment comment April 2009

The comment(s) below were originally left at Talk:14-3-3 protein/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

This article lacks necessary citations. States that elevated 14-3-3 protein levels in CSF have been found in patients with CJD - needs to be cited.

Last edited at 18:28, 29 April 2009 (UTC).

No mention of 14-3-3 shuttling

14-3-3 shuttling is mentioned in DDIT4 and some refs. Shuttling implies movement between what and what ? - Rod57 (talk) 10:42, 23 October 2016 (UTC)[reply]