From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Protein sprouty homolog 3protein that in humans is encoded by the SPRY3 gene .[ 3] [ 4]
The SPRY3 gene is one of the genes found in the pseudoautosomal regions of the human sex chromosomes (i.e. those 19 genes that are found on both the X and Y chromosome). It is located in the PAR2 region.
Ciccodicola A, D'Esposito M, Esposito T, et al. (2000). "Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region" . Hum. Mol. Genet . 9 (3): 395–401. doi :10.1093/hmg/9.3.395 PMID 10655549 . Lim J, Wong ES, Ong SH, et al. (2000). "Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain" . J. Biol. Chem . 275 (42): 32837–45. doi :10.1074/jbc.M002156200 PMID 10887178 . Lim J, Yusoff P, Wong ES, et al. (2002). "The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes" . Mol. Cell. Biol . 22 (22): 7953–66. doi :10.1128/MCB.22.22.7953-7966.2002 . PMC 134720 PMID 12391162 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Anteby EY, Natanson-Yaron S, Greenfield C, et al. (2005). "Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching". Placenta . 26 (6): 476–83. doi :10.1016/j.placenta.2004.08.008 . PMID 15950061 . De Bonis ML, Cerase A, Matarazzo MR, et al. (2006). "Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications" . Hum. Mol. Genet . 15 (7): 1123–32. doi :10.1093/hmg/ddl027 PMID 16500999 . Cabrita MA, Jäggi F, Widjaja SP, Christofori G (2006). "A functional interaction between sprouty proteins and caveolin-1" . J. Biol. Chem . 281 (39): 29201–2912. doi :10.1074/jbc.M603921200 PMID 16877379 .
