SERP1

SERP1
Identifiers
Aliases	SERP1, RAMP4, stress-associated endoplasmic reticulum protein 1, stress associated endoplasmic reticulum protein 1
External IDs	OMIM: 617674; MGI: 92638; HomoloGene: 8691; GeneCards: SERP1; OMA:SERP1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	150,603,228 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	58,433,313 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; corpus epididymis; ; body of pancreas; ; caput epididymis; ; bronchial epithelial cell; ; amniotic fluid; ; palpebral conjunctiva; ; mucosa of paranasal sinus; ; superficial temporal artery; ; lower lobe of lung;
	Top expressed in
	parotid gland; ; seminal vesicula; ; lacrimal gland; ; submandibular gland; ; crypt of lieberkuhn of small intestine; ; olfactory epithelium; ; lymph node; ; mesenteric lymph nodes; ; calvaria; ; pyloric antrum;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; cytosol; ribosome; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytoplasmic microtubule;
Biological process	skeletal system development; muscle organ morphogenesis; positive regulation of organ growth; post-embryonic development; positive regulation of translation; IRE1-mediated unfolded protein response; positive regulation of growth hormone secretion; glucose metabolic process; multicellular organism aging; protein transport; plasma membrane organization; positive regulation of insulin secretion; endoplasmic reticulum unfolded protein response; protein glycosylation;
	Sources:Amigo / QuickGO
Orthologs
	27230
	28146
	ENSG00000120742
	ENSMUSG00000027808
	Q9Y6X1
	Q9Z1W5
	NM_014445
	NM_030685
	NP_055260
	NP_109610
	Wikidata
View/Edit Human	View/Edit Mouse

Stress-associated endoplasmic reticulum protein 1 is a protein that in humans is encoded by the SERP1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120742 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027808 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yamaguchi A, Hori O, Stern DM, Hartmann E, Ogawa S, Tohyama M (Jan 2000). "Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation". J Cell Biol. 147 (6): 1195–204. doi:10.1083/jcb.147.6.1195. PMC 2168098. PMID 10601334.
^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
^ "Entrez Gene: SERP1 stress-associated endoplasmic reticulum protein 1".

Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000120742 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027808 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10601334-5] Yamaguchi A, Hori O, Stern DM, Hartmann E, Ogawa S, Tohyama M (Jan 2000). "Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation". J Cell Biol. 147 (6): 1195–204. doi:10.1083/jcb.147.6.1195. PMC 2168098. PMID 10601334.

[pmid11230166-6] Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.

[entrez-7] "Entrez Gene: SERP1 stress-associated endoplasmic reticulum protein 1".

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[3]

[4]

[5]

[6]

[7]

References

Further reading