SEPT11

SEPTIN11
Identifiers
Aliases	SEPTIN11, septin 11, SEPT11
External IDs	OMIM: 612887; MGI: 1277214; HomoloGene: 56800; GeneCards: SEPTIN11; OMA:SEPTIN11 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	77,040,384 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	93,324,306 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; Achilles tendon; ; stromal cell of endometrium; ; sural nerve; ; epithelium of colon; ; periodontal fiber; ; decidua; ; Brodmann area 9; ; right frontal lobe;
	Top expressed in
	Gonadal ridge; ; maxillary prominence; ; mandibular prominence; ; dermis; ; tail of embryo; ; abdominal wall; ; ventricular zone; ; genital tubercle; ; renal corpuscle; ; atrioventricular valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; molecular adaptor activity;
Cellular component	cytoplasm; axon; cell junction; dendritic spine; cell projection; synapse; cytoskeleton; stress fiber; postsynapse; glutamatergic synapse; GABA-ergic synapse; postsynaptic specialization of symmetric synapse; septin ring; microtubule cytoskeleton; septin complex; septin filament array;
Biological process	cell cycle; protein heterooligomerization; cell division; regulation of synapse organization; mitotic cytokinesis; septin ring assembly; cilium assembly; cytoskeleton-dependent cytokinesis;
	Sources:Amigo / QuickGO
Orthologs
	55752
	52398
	ENSG00000138758
	ENSMUSG00000058013
	Q9NVA2
	Q8C1B7
	NM_001306147; NM_018243
	NM_001009818; NM_001310669; NM_001310671; NM_001347377
	NP_001293076; NP_060713
	NP_001009818; NP_001297598; NP_001297600; NP_001334306
	Wikidata
View/Edit Human	View/Edit Mouse

Septin-11 is a protein that in humans is encoded by the SEPT11 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000138758 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058013 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kojima K, Sakai I, Hasegawa A, Niiya H, Azuma T, Matsuo Y, Fujii N, Tanimoto M, Fujita S (May 2004). "FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23)". Leukemia. 18 (5): 998–1005. doi:10.1038/sj.leu.2403334. PMID 14999297. S2CID 7182039.
^ Kim DS, Hubbard SL, Peraud A, Salhia B, Sakai K, Rutka JT (May 2004). "Analysis of mammalian septin expression in human malignant brain tumors". Neoplasia. 6 (2): 168–78. doi:10.1593/neo.03310. PMC 1502092. PMID 15140406.
^ "Entrez Gene: SEPT11 septin 11".

Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Wistow G, Bernstein SL, Wyatt MK, Fariss RN, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K (June 2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Molecular Vision. 8: 205–20. PMID 12107410.
Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (May 2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nature Biotechnology. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
Hanai N, Nagata K, Kawajiri A, Shiromizu T, Saitoh N, Hasegawa Y, Murakami S, Inagaki M (June 2004). "Biochemical and cell biological characterization of a mammalian septin, Sept11". FEBS Letters. 568 (1–3): 83–8. doi:10.1016/j.febslet.2004.05.030. PMID 15196925. S2CID 11315113.
Nagata K, Asano T, Nozawa Y, Inagaki M (December 2004). "Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11". The Journal of Biological Chemistry. 279 (53): 55895–904. doi:10.1074/jbc.M406153200. PMID 15485874.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K (October 2007). "SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling". Human Mutation. 28 (10): 1005–13. doi:10.1002/humu.20554. PMID 17546647. S2CID 40174453.
Xin X, Pache M, Zieger B, Bartsch I, Prünte C, Flammer J, Meyer P (November 2007). "Septin expression in proliferative retinal membranes". The Journal of Histochemistry and Cytochemistry. 55 (11): 1089–94. doi:10.1369/jhc.7A7188.2007. PMC 3957527. PMID 17625225.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000138758 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058013 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14999297-5] Kojima K, Sakai I, Hasegawa A, Niiya H, Azuma T, Matsuo Y, Fujii N, Tanimoto M, Fujita S (May 2004). "FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23)". Leukemia. 18 (5): 998–1005. doi:10.1038/sj.leu.2403334. PMID 14999297. S2CID 7182039.

[pmid15140406-6] Kim DS, Hubbard SL, Peraud A, Salhia B, Sakai K, Rutka JT (May 2004). "Analysis of mammalian septin expression in human malignant brain tumors". Neoplasia. 6 (2): 168–78. doi:10.1593/neo.03310. PMC 1502092. PMID 15140406.

[entrez-7] "Entrez Gene: SEPT11 septin 11".

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References

Further reading