SCYL3

SCYL3
Identifiers
Aliases	SCYL3, PACE-1, PACE1, SCY1 like pseudokinase 3
External IDs	OMIM: 608192; MGI: 1921385; HomoloGene: 10706; GeneCards: SCYL3; OMA:SCYL3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	169,894,267 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	163,782,695 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; secondary oocyte; ; amniotic fluid; ; pancreatic ductal cell; ; epithelium of nasopharynx; ; palpebral conjunctiva; ; Epithelium of choroid plexus; ; Achilles tendon; ; endothelial cell; ; testicle;
	Top expressed in
	superior cervical ganglion; ; spermatocyte; ; Paneth cell; ; granulocyte; ; otolith organ; ; facial motor nucleus; ; utricle; ; dorsal striatum; ; substantia nigra; ; mesenteric lymph nodes;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; ATP binding; kinase activity;
Cellular component	cytoplasm; Golgi apparatus; cell projection; lamellipodium;
Biological process	protein phosphorylation; cell migration;
	Sources:Amigo / QuickGO
Orthologs
	57147
	240880
	ENSG00000000457
	ENSMUSG00000026584
	Q8IZE3
	Q9DBQ7
	NM_020423; NM_181093
	NM_001286002; NM_001286003; NM_028776; NM_001357426
	NP_065156; NP_851607
	NP_001272931; NP_001272932; NP_083052; NP_001344355
	Wikidata
View/Edit Human	View/Edit Mouse

Protein-associating with the carboxyl-terminal domain of ezrin is a protein that in humans is encoded by the SCYL3 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000000457 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026584 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sullivan A, Uff CR, Isacke CM, Thorne RF (Mar 2003). "PACE-1, a novel protein that interacts with the C-terminal domain of ezrin". Exp Cell Res. 284 (2): 224–38. doi:10.1016/S0014-4827(02)00054-X. PMID 12651155.
^ "Entrez Gene: SCYL3 SCY1-like 3 (S. cerevisiae)".

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Maurer-Stroh S, Gouda M, Novatchkova M, et al. (2004). "MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins". Genome Biol. 5 (3): R21. doi:10.1186/gb-2004-5-3-r21. PMC 395771. PMID 15003124.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000000457 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026584 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12651155-5] Sullivan A, Uff CR, Isacke CM, Thorne RF (Mar 2003). "PACE-1, a novel protein that interacts with the C-terminal domain of ezrin". Exp Cell Res. 284 (2): 224–38. doi:10.1016/S0014-4827(02)00054-X. PMID 12651155.

[entrez-6] "Entrez Gene: SCYL3 SCY1-like 3 (S. cerevisiae)".

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References

Further reading