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Robert Shanks (pharmacologist)

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Robert Gray Robin Shanks CBE (born 4 April 1934) is a British retired clinical pharmacologist, specialising in Beta adrenergic blocking drugs. He was made a Commander of the Order of the British Empire (CBE) in the 1997 New Year Honours, For Services to Medicine.[1]

Shanks was the first person to give a beta blocking drug (DCI, dichloroisoprenaline) to a person in 1961/62 to study its effects on cardiovascular responses to catecholamines and stress.[2] Jointly with Sir James Black (Nobel Prize winner in 1988) he discovered the beta-blocking drug, propranolol, in 1962.[3] In 1964 he classified beta adrenergic receptors in beta one and beta two and as a result developed the first drug (practoLol) to selectively block beta one receptors.[4] Subsequently he spent 30 years studying the properties and clinical pharmacology and clinical use of beta blocking and other cardiovascular drugs.

He published many research articles on beta blockers during his tenure at Queens University Belfast.[5]

He was elected a Member of the Royal Irish Academy (MRIA) in 1986[6] [7]

He was Pro-Vice-Chancellor from 1991 to 1997 and acting Vice-Chancellor in 1998 of Queens University Belfast.[8] Since his retirement in 1998 he has been Emeritus Whitla Professor of Therapeutics and Pharmacology, Queens University Belfast.[9][10]

References

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  1. ^ "The London Gazette". Supplement. No. 54625. 30 December 1996.
  2. ^ Love, AHG; Shanks, RG (June 1962). "The relationship between the onset of sweating and vasodilatation in the forearm during body heating". The Journal of Physiology. 162 (1): 121–128. doi:10.1113/jphysiol.1962.sp006918. PMC 1359643. PMID 14466872.
  3. ^ Black, JW; Crowther, AF; Shanks, RG; Smith, LH; Dornhorst, AC (May 16, 1964). "A New Adrenergic". The Lancet. 238 (7342): 1080–1081. doi:10.1016/S0140-6736(64)91275-9. PMID 14132613.
  4. ^ Dunlop, D; Shanks, RG (Jan 1968). "Selective blockade of adrenoceptive beta receptors in the heart". British Journal of Pharmacology. 32 (1): 201–218. doi:10.1111/j.1476-5381.1968.tb00444.x. PMC 1570292. PMID 4384337.
  5. ^ "Robin G. Shanks's research while affiliated with Queen's University Belfast and other places". ResearchGate. Retrieved 16 January 2022.
  6. ^ "Robert Gray Shanks". ria.ie. 19 October 2015.
  7. ^ "Members of Royal Irish Academy". ria.ie. 27 August 2020.
  8. ^ "Notable Alumni". qub.ac.uk.
  9. ^ "Remembering Sir Peter Froggatt". qub.ac.uk.
  10. ^ Power, Gerry (2021-10-08). "RETURN TO QUEEN'S – 70 YEARS AFTER STARTING AS UNDERGRADUATE STUDENTS". Queen's University Belfast Alumni Relations. Retrieved 2022-04-28.