RABL6

RABL6
Identifiers
Aliases	RABL6, C9orf86, PARF, RBEL1, pp8875, RAB, member RAS oncogene family-like 6, RAB, member RAS oncogene family like 6
External IDs	OMIM: 610615; MGI: 2442633; HomoloGene: 11674; GeneCards: RABL6; OMA:RABL6 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	136,841,187 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	25,498,533 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; nucleus accumbens; ; apex of heart; ; right frontal lobe; ; anterior cingulate cortex; ; gastrocnemius muscle; ; caudate nucleus; ; muscle of thigh; ; pylorus; ; amygdala;
	Top expressed in
	tail of embryo; ; interventricular septum; ; genital tubercle; ; superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh; ; internal carotid artery; ; cerebellar cortex; ; lacrimal gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity;
Cellular component	cytoplasm; nucleus; centrosome; cytosol; intracellular anatomical structure;
Biological process	small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	55684
	227624
	ENSG00000196642
	ENSMUSG00000015087
	Q3YEC7
	Q5U3K5
	NM_024718; NM_001173988; NM_001173989; NM_017995
	NM_001024616
	NP_001167459; NP_001167460; NP_078994
	NP_001019787
	Wikidata
View/Edit Human	View/Edit Mouse

Rab-like protein 6 is a protein that in humans is encoded by the RABL6 gene.^[5]^[6]^[7]^[8]

Interactions

RABL6 has been shown to interact with MDFI.^[9]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196642 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015087 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tompkins V, Hagen J, Zediak VP, Quelle DE (Mar 2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi:10.4161/cc.5.6.2560. PMID 16582619.
^ Montalbano J, Jin W, Sheikh MS, Huang Y (Dec 2007). "RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer". The Journal of Biological Chemistry. 282 (52): 37640–9. doi:10.1074/jbc.M704760200. PMID 17962191.
^ Montalbano J, Lui K, Sheikh MS, Huang Y (Jul 2009). "Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation". The Journal of Biological Chemistry. 284 (27): 18129–42. doi:10.1074/jbc.M109.009597. PMC 2709392. PMID 19433581.
^ "Entrez Gene: C9orf86 chromosome 9 open reading frame 86".
^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

External links

Human RABL6 genome location and RABL6 gene details page in the UCSC Genome Browser.

Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Cui YP, Wang JB, Zhang XY, Bi MX, Guo LP, Lu SH (Sep 2003). "Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene". World Journal of Gastroenterology. 9 (9): 1892–6. doi:10.3748/wjg.v9.i9.1892. PMC 4656638. PMID 12970870.
Cui Y, Wang J, Zhang X, Lang R, Bi M, Guo L, Lu SH (Mar 2003). "ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis". Biochemical and Biophysical Research Communications. 302 (4): 904–15. doi:10.1016/S0006-291X(03)00122-0. PMID 12646258.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000196642 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000015087 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16582619-5] Tompkins V, Hagen J, Zediak VP, Quelle DE (Mar 2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi:10.4161/cc.5.6.2560. PMID 16582619.

[pmid17962191-6] Montalbano J, Jin W, Sheikh MS, Huang Y (Dec 2007). "RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer". The Journal of Biological Chemistry. 282 (52): 37640–9. doi:10.1074/jbc.M704760200. PMID 17962191.

[pmid19433581-7] Montalbano J, Lui K, Sheikh MS, Huang Y (Jul 2009). "Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation". The Journal of Biological Chemistry. 284 (27): 18129–42. doi:10.1074/jbc.M109.009597. PMC 2709392. PMID 19433581.

[entrez-8] "Entrez Gene: C9orf86 chromosome 9 open reading frame 86".

[pmid16189514-9] Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

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[9]

Interactions

References

External links

Further reading