Portal:Medicine

The Medicine Portal

The color fresco Care of The Sick by Domenico di Bartolo, 1441–1442, depicting the Santa Maria della Scala hospital in Siena, Italy

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others.

Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). For example, while stitching technique for sutures is an art learned through practice, knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science.

Prescientific forms of medicine, now known as traditional medicine or folk medicine, remain commonly used in the absence of scientific medicine and are thus called alternative medicine. Alternative treatments outside of scientific medicine with ethical, safety and efficacy concerns are termed quackery. (Full article...)

Featured articles -

Featured articles are displayed here, which represent some of the best content on English Wikipedia.

---

• 
  
  

  

  In 1942–43 the UK Government carried out extensive testing for oxygen toxicity in divers. The chamber is pressurised with air to 3.7 bar. The subject in the centre is breathing 100% oxygen from a mask.

  
  Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen (O
  ₂) at increased partial pressures. Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs, and eyes. Historically, the central nervous system condition was called the Paul Bert effect, and the pulmonary condition the Lorrain Smith effect, after the researchers who pioneered the discoveries and descriptions in the late 19th century. Oxygen toxicity is a concern for underwater divers, those on high concentrations of supplemental oxygen, and those undergoing hyperbaric oxygen therapy.
  
  The result of breathing increased partial pressures of oxygen is hyperoxia, an excess of oxygen in body tissues. The body is affected in different ways depending on the type of exposure. Central nervous system toxicity is caused by short exposure to high partial pressures of oxygen at greater than atmospheric pressure. Pulmonary and ocular toxicity result from longer exposure to increased oxygen levels at normal pressure. Symptoms may include disorientation, breathing problems, and vision changes such as myopia. Prolonged exposure to above-normal oxygen partial pressures, or shorter exposures to very high partial pressures, can cause oxidative damage to cell membranes, collapse of the alveoli in the lungs, retinal detachment, and seizures. Oxygen toxicity is managed by reducing the exposure to increased oxygen levels. Studies show that, in the long term, a robust recovery from most types of oxygen toxicity is possible. (Full article...)
• 
  
  

  

  Buruli ulcer lesions. Top-left, an early ulcer. Top-right, a larger ulcer across the lower arm and wrist. Bottom, a large ulcer on the thigh.

  
  Buruli ulcer (/bəˈruːli/) is an infectious disease characterized by the development of painless open wounds. The disease is limited to certain areas of the world, most cases occurring in Sub-Saharan Africa and Australia. The first sign of infection is a small painless nodule or area of swelling, typically on the arms or legs. The nodule grows larger over days to weeks, eventually forming an open ulcer. Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability.
  
  Buruli ulcer is caused by skin infection with bacteria called Mycobacterium ulcerans. The mechanism by which M. ulcerans is transmitted from the environment to humans is not known, but may involve the bite of an aquatic insect or the infection of open wounds. Once in the skin, M. ulcerans grows and releases the toxin mycolactone, which blocks the normal function of cells, resulting in tissue death and immune suppression at the site of the ulcer. (Full article...)
• 
  
  

  

  Sadler c. 1915

  
  William Samuel Sadler (June 24, 1875 – April 26, 1969) was an American surgeon, self-trained psychiatrist, and author who helped publish The Urantia Book. The book is said to have resulted from Sadler's relationship with a man through whom he believed celestial beings spoke at night. It drew a following of people who studied its teachings.
  
  A native of Indiana, Sadler moved to Michigan as a teenager to work at the Battle Creek Sanitarium. There he met the physician and health-food promoter John Harvey Kellogg, co-inventor of corn flakes breakfast cereal, who became his mentor. Sadler married Kellogg's niece, Lena Celestia Kellogg, in 1897. He worked for several Christian organizations and attended medical school, graduating in 1906. Sadler practiced medicine in Chicago with his wife, who was also a physician. He joined several medical associations and taught at the McCormick Theological Seminary. Although he was a committed member of the Seventh-day Adventist Church for almost twenty years, he left the denomination after it disfellowshipped his wife's uncle, John Harvey Kellogg, in 1907. Sadler and his wife became speakers on the Chautauqua adult education circuit in 1907, and he became a highly paid, popular orator. He eventually wrote over 40 books on a variety of medical and spiritual topics advocating a holistic approach to health. Sadler extolled the value of prayer and religion but was skeptical of mediums, assisting debunker Howard Thurston, and embraced the scientific consensus on evolution. (Full article...)
• 

  

  
  Amphetamine (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine. Amphetamine was discovered as a chemical in 1887 by Lazăr Edeleanu, and then as a drug in the late 1920s. It exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers in their pure amine forms. The term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Historically, it has been used to treat nasal congestion and depression. Amphetamine is also used as an athletic performance enhancer and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. It is a prescription drug in many countries, and unauthorized possession and distribution of amphetamine are often tightly controlled due to the significant health risks associated with recreational use.
  
  The first amphetamine pharmaceutical was Benzedrine, a brand which was used to treat a variety of conditions. Currently, pharmaceutical amphetamine is prescribed as racemic amphetamine, Adderall, dextroamphetamine, or the inactive prodrug lisdexamfetamine. Amphetamine increases monoamine and excitatory neurotransmission in the brain, with its most pronounced effects targeting the norepinephrine and dopamine neurotransmitter systems. (Full article...)
• 
  Dark Archives: A Librarian's Investigation into the Science and History of Books Bound in Human Skin is a 2020 non-fiction book by the medical librarian and death-positive advocate Megan Rosenbloom. Dealing with anthropodermic bibliopegy, the binding of books in human skin, it expounds upon Rosenbloom's research on such books and their historical, ethical, and cultural implications.
  
  The book focuses on the relationship between anthropodermic bibliopegy and the history of medicine; most confirmed cases of such books were created or owned by medical professionals, in contrast to common stereotypes that they were associated with Nazi Germany, serial killers, or the French Revolution. Rosenbloom discusses how the practice reflects the changing attitudes towards consent, ownership, and disposal of human bodies, and how the history of anthropodermic books intertwines with the history of medical ethics as a field. She interviews librarians, archivists, collectors, and experts on the topic, and examines notable examples of such books and their origins. Though Rosenbloom supports the preservation and maintenance of anthropodermic books, Dark Archives also covers arguments to the contrary, such as those espoused by Princeton University Library senior librarian Paul Needham. (Full article...)
• 
  
  

  

  Anti-FGM road sign near Kapchorwa, Uganda, 2004

  
  Female genital mutilation (FGM) (also known as female genital cutting, female genital mutilation/cutting (FGM/C) and female circumcision) is the cutting or removal of some or all of the vulva for non-medical reasons. FGM prevalence varies worldwide, but is majorly present in some countries of Africa, Asia and Middle East, and within their diasporas. As of 2024, UNICEF estimates that worldwide 230 million girls and women (144 million in Africa, 80 million in Asia, 6 million in Middle East, and 1-2 million in other parts of the world) had been subjected to one or more types of FGM.
  
  Typically carried out by a traditional cutter using a blade, FGM is conducted from days after birth to puberty and beyond. In half of the countries for which national statistics are available, most girls are cut before the age of five. Procedures differ according to the country or ethnic group. They include removal of the clitoral hood (type 1-a) and clitoral glans (1-b); removal of the inner labia (2-a); and removal of the inner and outer labia and closure of the vulva (type 3). In this last procedure, known as infibulation, a small hole is left for the passage of urine and menstrual fluid, the vagina is opened for intercourse and opened further for childbirth. (Full article...)
• 
  
  

  

  Scanning electron micrograph of Escherichia coli rods

  
  Bacteria (/bækˈtɪəriə/ ; sg.: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in mutualistic, commensal and parasitic relationships with plants and animals. Most bacteria have not been characterised and there are many species that cannot be grown in the laboratory. The study of bacteria is known as bacteriology, a branch of microbiology.
  
  Like all animals, humans carry vast numbers (approximately 10¹³ to 10¹⁴) of bacteria. Most are in the gut, though there are many on the skin. Most of the bacteria in and on the body are harmless or rendered so by the protective effects of the immune system, and many are beneficial, particularly the ones in the gut. However, several species of bacteria are pathogenic and cause infectious diseases, including cholera, syphilis, anthrax, leprosy, tuberculosis, tetanus and bubonic plague. The most common fatal bacterial diseases are respiratory infections. Antibiotics are used to treat bacterial infections and are also used in farming, making antibiotic resistance a growing problem. Bacteria are important in sewage treatment and the breakdown of oil spills, the production of cheese and yogurt through fermentation, the recovery of gold, palladium, copper and other metals in the mining sector (biomining, bioleaching), as well as in biotechnology, and the manufacture of antibiotics and other chemicals. (Full article...)
• 
  
  

  

  Georges Gilles de la Tourette (1857–1904),
  namesake of Tourette syndrome

  
  Tourette syndrome or Tourette's syndrome (abbreviated as TS or Tourette's) is a common neurodevelopmental disorder that begins in childhood or adolescence. It is characterized by multiple movement (motor) tics and at least one vocal (phonic) tic. Common tics are blinking, coughing, throat clearing, sniffing, and facial movements. These are typically preceded by an unwanted urge or sensation in the affected muscles known as a premonitory urge, can sometimes be suppressed temporarily, and characteristically change in location, strength, and frequency. Tourette's is at the more severe end of a spectrum of tic disorders. The tics often go unnoticed by casual observers.
  
  Tourette's was once regarded as a rare and bizarre syndrome and has popularly been associated with coprolalia (the utterance of obscene words or socially inappropriate and derogatory remarks). It is no longer considered rare; about 1% of school-age children and adolescents are estimated to have Tourette's, though coprolalia occurs only in a minority. There are no specific tests for diagnosing Tourette's; it is not always correctly identified, because most cases are mild, and the severity of tics decreases for most children as they pass through adolescence. Therefore, many go undiagnosed or may never seek medical attention. Extreme Tourette's in adulthood, though sensationalized in the media, is rare, but for a small minority, severely debilitating tics can persist into adulthood. Tourette's does not affect intelligence or life expectancy. (Full article...)
• 
  
  

  

  The location and development of endometrial cancer

  
  Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb). It is the result of the abnormal growth of cells that have the ability to invade or spread to other parts of the body. The first sign is most often vaginal bleeding not associated with a menstrual period. Other symptoms include pain with urination, pain during sexual intercourse, or pelvic pain. Endometrial cancer occurs most commonly after menopause.
  
  
  Approximately 40% of cases are related to obesity. Endometrial cancer is also associated with excessive estrogen exposure, high blood pressure and diabetes. Whereas taking estrogen alone increases the risk of endometrial cancer, taking both estrogen and a progestogen in combination, as in most birth control pills, decreases the risk. Between two and five percent of cases are related to genes inherited from the parents. Endometrial cancer is sometimes called "uterine cancer", although it is distinct from other forms of cancer of the uterus such as cervical cancer, uterine sarcoma, and trophoblastic disease. The most frequent type of endometrial cancer is endometrioid carcinoma, which accounts for more than 80% of cases. Endometrial cancer is commonly diagnosed by endometrial biopsy or by taking samples during a procedure known as dilation and curettage. A pap smear is not typically sufficient to show endometrial cancer. Regular screening in those at normal risk is not called for. (Full article...)
• 
  
  

  

  Meninges of the central nervous system: dura mater, arachnoid mater, and pia mater.

  
  Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, intense headache, vomiting and neck stiffness and occasionally photophobia. Other symptoms include confusion or altered consciousness, nausea, and an inability to tolerate light or loud noises. Young children often exhibit only nonspecific symptoms, such as irritability, drowsiness, or poor feeding. A non-blanching rash (a rash that does not fade when a glass is rolled over it) may also be present.
  
  The inflammation may be caused by infection with viruses, bacteria, fungi or parasites. Non-infectious causes include malignancy (cancer), subarachnoid hemorrhage, chronic inflammatory disease (sarcoidosis) and certain drugs. Meningitis can be life-threatening because of the inflammation's proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. A lumbar puncture, in which a needle is inserted into the spinal canal to collect a sample of cerebrospinal fluid (CSF), can diagnose or exclude meningitis. (Full article...)
• 
  
  

  

  Electron micrograph of H. pylori possessing multiple flagella (negative staining)

  
  Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, flagellated, helical bacterium. Mutants can have a rod or curved rod shape that exhibits less virulence. Its helical body (from which the genus name Helicobacter derives) is thought to have evolved to penetrate the mucous lining of the stomach, helped by its flagella, and thereby establish infection. The bacterium was first identified as the causal agent of gastric ulcers in 1983 by Australian physician-scientists Barry Marshall and Robin Warren. In 2005, they were awarded the Nobel Prize in Physiology or Medicine for their discovery.
  
  Infection of the stomach with H. pylori is not the cause of illness itself: over half of the global population is infected, but most individuals are asymptomatic. Persistent colonization with more virulent strains can induce a number of gastric and non-gastric disorders. Gastric disorders due to infection begin with gastritis, or inflammation of the stomach lining. When infection is persistent, the prolonged inflammation will become chronic gastritis. Initially, this will be non-atrophic gastritis, but the damage caused to the stomach lining can bring about the development of atrophic gastritis and ulcers within the stomach itself or the duodenum (the nearest part of the intestine). At this stage, the risk of developing gastric cancer is high. However, the development of a duodenal ulcer confers a comparatively lower risk of cancer. Helicobacter pylori is a class 1 carcinogenic bacteria, and potential cancers include gastric MALT lymphoma and gastric cancer. Infection with H. pylori is responsible for an estimated 89% of all gastric cancers and is linked to the development of 5.5% of all cases cancers worldwide. H. pylori is the only bacterium known to cause cancer. (Full article...)
• 

  

  Testing for ketone bodies in urine

  
  
  The ketogenic diet is a high-fat, adequate-protein, low-carbohydrate dietary therapy that in conventional medicine is used mainly to treat hard-to-control (refractory) epilepsy in children. The diet forces the body to burn fats rather than carbohydrates.
  
  Normally, carbohydrates in food are converted into glucose, which is then transported around the body and is important in fueling brain function. However, if only a little carbohydrate remains in the diet, the liver converts fat into fatty acids and ketone bodies, the latter passing into the brain and replacing glucose as an energy source. An elevated level of ketone bodies in the blood (a state called ketosis) eventually lowers the frequency of epileptic seizures. Around half of children and young people with epilepsy who have tried some form of this diet saw the number of seizures drop by at least half, and the effect persists after discontinuing the diet. Some evidence shows that adults with epilepsy may benefit from the diet and that a less strict regimen, such as a modified Atkins diet, is similarly effective. Side effects may include constipation, high cholesterol, growth slowing, acidosis, and kidney stones. (Full article...)
• 
  
  

  

  Cloth embroidered by a person diagnosed with schizophrenia

  
  Schizophrenia is a mental disorder characterized variously by hallucinations (typically, hearing voices), delusions, disorganized thinking and behavior, and flat or inappropriate affect. Symptoms develop gradually and typically begin during young adulthood and are never resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a psychiatric history that includes the person's reported experiences, and reports of others familiar with the person. For a diagnosis of schizophrenia, the described symptoms need to have been present for at least six months (according to the DSM-5) or one month (according to the ICD-11). Many people with schizophrenia have other mental disorders, especially mood disorders, anxiety disorders, and obsessive–compulsive disorder.
  
  
  About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. In 2017, there were an estimated 1.1 million new cases and in 2022 a total of 24 million cases globally. Males are more often affected and on average have an earlier onset than females. The causes of schizophrenia may include genetic and environmental factors. Genetic factors include a variety of common and rare genetic variants. Possible environmental factors include being raised in a city, childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father, and poor nutrition during pregnancy. (Full article...)
• 
  Taare Zameen Par (lit. 'Stars on Earth'), also known as Like Stars on Earth in English, is a 2007 Indian Hindi-language psychological drama film produced and directed by Aamir Khan. It stars Khan himself, with Darsheel Safary, Tanay Chheda, Vipin Sharma and Tisca Chopra. It explores the life and imagination of Ishaan (Safary), an artistically gifted 8-year-old boy whose poor academic performance leads his parents to send him to a boarding school, where a new art teacher Nikumbh (Khan) suspects that he is dyslexic and helps him to overcome his reading disorder.
  
  Creative director and writer Amole Gupte developed the idea with his wife Deepa Bhatia, who was the film's editor. Shankar–Ehsaan–Loy composed the score, and Prasoon Joshi wrote the lyrics for many of the songs. Principal photography took place in Mumbai, and in Panchgani's New Era High School, where some of the school's students participated in the filming. (Full article...)
• 

  

  Fluoridation does not affect the appearance, taste or smell of drinking water.

  
  
  Water fluoridation is the addition of fluoride to a public water supply to reduce tooth decay. Fluoridated water contains fluoride at a level that is effective for preventing cavities; this can occur naturally or by adding fluoride. Fluoridated water operates on tooth surfaces: in the mouth, it creates low levels of fluoride in saliva, which reduces the rate at which tooth enamel demineralizes and increases the rate at which it remineralizes in the early stages of cavities. Typically a fluoridated compound is added to drinking water, a process that in the U.S. costs an average of about $1.32 per person-year. Defluoridation is needed when the naturally occurring fluoride level exceeds recommended limits. In 2011, the World Health Organization suggested a level of fluoride from 0.5 to 1.5 mg/L (milligrams per litre), depending on climate, local environment, and other sources of fluoride. In 2024, the Department of Health and Human Services' National Toxicology Program found that water fluoridation levels above 1.5 mg/L are associated with lower IQ in children. In 2024, U.S. court rulings have raised concerns about the potential health risks of water fluoridation, including findings by the EPA and new risk assessments that suggest the benefits may be waning. Bottled water typically has unknown fluoride levels.
  
  
  Tooth decay remains a major public health concern in most industrialized countries, affecting 60–90% of schoolchildren and the vast majority of adults. Water fluoridation reduces cavities in children, while efficacy in adults is less clear. A Cochrane review estimates a reduction in cavities when water fluoridation was used by children who had no access to other sources of fluoride to be 35% in baby teeth and 26% in permanent teeth. Most European countries have experienced substantial declines in tooth decay, though milk and salt fluoridation is widespread in lieu of water fluoridation. Some studies suggest that water fluoridation, particularly in industrialized nations, may be unnecessary because topical fluorides (such as in toothpaste) are widely used, and caries rates have become low. (Full article...)

Selected image –

A mature human spermatozoon

Photo credit: User:LadyofHats

WikiProject

Get involved by joining WikiProject Medicine. We discuss collaborations and all manner of issues on our talk page.

Related portals

Good articles -

These are Good articles, which meet a core set of high editorial standards.

---

• 
  
  

  

  Raw sesame seeds with sesame plants in background

  
  A food allergy to sesame (Sesamum indicum) seeds has prevalence estimates in the range of 0.1–0.2% of the general population, and are higher in the Middle East and other countries where sesame seeds are used in traditional foods. Reporting of sesame seed allergy has increased in the 21st century, either due to a true increase from exposure to more sesame foods or due to an increase in awareness. Increasing sesame allergy rates have induced more countries to regulate food labels to identify sesame ingredients in products and the potential for allergy. In the United States, sesame became the ninth food allergen with mandatory labeling, effective 1 January 2023.
  
  The allergic reaction is an immune hypersensitivity to proteins and lipophilic proteins in sesame seeds and foods made with sesame seeds, including food-grade sesame oil. Symptoms can be either rapid or gradual in onset, occurring over minutes to days. Rapid allergic reaction may include anaphylaxis, a potentially life-threatening condition requiring treatment with epinephrine. Other, slower presentations may include atopic dermatitis or inflammation of the esophagus. For food labeling requirements established in many countries, sesame labeling is required in addition to the eight most common food allergens, responsible for 90% of allergic reactions to foods: cow's milk, eggs, wheat, shellfish, peanuts, tree nuts, fish, and soy beans. (Full article...)
• 
  
  

  

  A kidney stone, 8 millimeters (0.3 in) in diameter

  
  Kidney stone disease, also known as renal calculus disease, nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material (renal calculus) develops in the urinary tract. Renal calculi typically form in the kidney and leave the body in the urine stream. A small calculus may pass without causing symptoms. If a stone grows to more than 5 millimeters (0.2 inches), it can cause blockage of the ureter, resulting in sharp and severe pain in the lower back that often radiates downward to the groin (renal colic). A calculus may also result in blood in the urine, vomiting, or painful urination. About half of people who have had a renal calculus are likely to have another within ten years.
  
  
  Most calculi form by a combination of genetics and environmental factors. Risk factors include high urine calcium levels, obesity, certain foods, some medications, calcium supplements, hyperparathyroidism, gout and not drinking enough fluids. Calculi form in the kidney when minerals in urine are at high concentration. The diagnosis is usually based on symptoms, urine testing, and medical imaging. Blood tests may also be useful. Calculi are typically classified by their location: nephrolithiasis (in the kidney), ureterolithiasis (in the ureter), cystolithiasis (in the bladder), or by what they are made of (calcium oxalate, uric acid, struvite, cystine). (Full article...)
• 

  

  John M. Wieting (1903)

  
  John Manchester Wieting (February 8, 1817 – February 13, 1888) was an American lecturer and philanthropist. He spent his early years as a teacher and then as an engineer and grader. After moving to Syracuse, New York, he read medicine to become a physician. After purchasing anatomical models he began giving lectures across upstate New York, gradually expanding the reach and the size of his lectures. They were extravagant affairs, and Wieting became known as one of the era's most prominent anatomical lecturers.
  
  He retired from lecturing at the age of 45 in 1862, and spent his remaining years traveling the world and engaging in philanthropic efforts, mainly aimed at the development of Syracuse. Wieting funded construction of the Wieting Opera House in the city, which was open until 1930 and became a place for Broadway plays to be tried out. He has been cited by several scholars as one of the most famous anatomical lecturers of his era. (Full article...)
• 
  Linda Jane Laubenstein (May 21, 1947 – August 15, 1992) was an American physician and early HIV/AIDS researcher. She was among the first doctors in the United States to recognize the AIDS epidemic of the early 1980s; she co-authored the first article linking AIDS with Kaposi's sarcoma.
  
  Laubenstein was raised in Barrington, Rhode Island, where a childhood bout of polio left her paraplegic and using a wheelchair for the rest of her life. She graduated from Barnard College in 1969 and received her medical degree from New York University School of Medicine, where she specialized in hematology and oncology. She went on to become a clinical professor before leaving to focus on treating AIDS patients in her private practice. In addition to her medical work, she was an outspoken AIDS activist and co-founded a non-profit organization, Multitasking, which provided employment to people with AIDS. (Full article...)
• 
  Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogen, that is, an inactive enzyme. The activated form plays an important role in regulating anticoagulation, inflammation, and cell death and maintaining the permeability of blood vessel walls in humans and other animals. Activated protein C (APC) performs these operations primarily by proteolytically inactivating proteins Factor V_a and Factor VIII_a. APC is classified as a serine protease since it contains a residue of serine in its active site. In humans, protein C is encoded by the PROC gene, which is found on chromosome 2.
  
  The zymogenic form of protein C is a vitamin K-dependent glycoprotein that circulates in blood plasma. Its structure is that of a two-chain polypeptide consisting of a light chain and a heavy chain connected by a disulfide bond. The protein C zymogen is activated when it binds to thrombin, another protein heavily involved in coagulation, and protein C's activation is greatly promoted by the presence of thrombomodulin and endothelial protein C receptors (EPCRs). Because of EPCR's role, activated protein C is found primarily near endothelial cells (i.e., those that make up the walls of blood vessels), and it is these cells and leukocytes (white blood cells) that APC affects. Because of the crucial role that protein C plays as an anticoagulant, those with deficiencies in protein C, or some kind of resistance to APC, suffer from a significantly increased risk of forming dangerous blood clots (thrombosis). (Full article...)
• 
  Iodine is a chemical element; it has symbol I and atomic number 53. The heaviest of the stable halogens, it exists at standard conditions as a semi-lustrous, non-metallic solid that melts to form a deep violet liquid at 114 °C (237 °F), and boils to a violet gas at 184 °C (363 °F). The element was discovered by the French chemist Bernard Courtois in 1811 and was named two years later by Joseph Louis Gay-Lussac, after the Ancient Greek Ιώδης, meaning 'violet'.
  
  Iodine occurs in many oxidation states, including iodide (I⁻), iodate (IO⁻
  ₃), and the various periodate anions. As the heaviest essential mineral nutrient, iodine is required for the synthesis of thyroid hormones. Iodine deficiency affects about two billion people and is the leading preventable cause of intellectual disabilities. (Full article...)
• 
  BGR-34 (Blood Glucose Regulator-34) is an Ayurvedic-derived product that is sold in India as an over-the-counter pill for the management of type 2 diabetes. It was developed in 2015 by two government-owned laboratories and launched commercially in 2016. It has been tested in only one, modest-sized, human trial. The drug has been heavily criticized, and without more clinical trials, its efficacy remains unproven. The manufacturers have refused to acknowledge the claims of inefficacy and other concerns. (Full article...)
• 
  
  

  

  A blue circle is the universal symbol of diabetes.

  
  Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss. Other symptoms include increased hunger, having a sensation of pins and needles, and sores (wounds) that heal slowly. Symptoms often develop slowly. Long-term complications from high blood sugar include heart disease, stroke, diabetic retinopathy, which can result in blindness, kidney failure, and poor blood flow in the lower-limbs, which may lead to amputations. The sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon.
  
  
  Type 2 diabetes primarily occurs as a result of obesity and lack of exercise. Some people are genetically more at risk than others. (Full article...)
• 

  

  Wasp stinger with a droplet of venom

  
  
  Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved venom apparatus, such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism.
  
  Venom has evolved in terrestrial and marine environments and in a wide variety of animals: both predators and prey, and both vertebrates and invertebrates. Venoms kill through the action of at least four major classes of toxin, namely necrotoxins and cytotoxins, which kill cells; neurotoxins, which affect nervous systems; myotoxins, which damage muscles; and haemotoxins, which disrupt blood clotting. Venomous animals cause tens of thousands of human deaths per year. (Full article...)
• 
  
  

  

  Ryan in 2023

  
  Monique Marie Ryan (born 20 January 1967) is an Australian politician and former paediatric neurologist. She is currently the independent Member of Parliament for the Division of Kooyong, Victoria, having won the seat at the 2022 federal election.
  
  Ryan completed her medical qualifications in Melbourne and Sydney, and Boston, Massachusetts, United States. She became director of neurology at Melbourne's Royal Children's Hospital in 2014. During her medical career, Ryan has published more than 150 peer-reviewed publications and supervised several clinical trials for neurological diseases. (Full article...)
• 
  
  

  

  Merrick, c. 1889

  
  Joseph Carey Merrick (5 August 1862 – 11 April 1890) was an English man known for his severe physical deformities. He was first exhibited at a freak show under the stage name "The Elephant Man", and then went to live at the London Hospital, in Whitechapel, after meeting Sir Frederick Treves, subsequently becoming well known in London society.
  
  Merrick was born in Leicester and began to develop abnormally before the age of five. His mother died when he was eleven, and his father soon remarried. Rejected by his father and stepmother, he left home and went to live with his uncle, Charles Merrick. In 1879, 17-year-old Merrick entered the Leicester Union Workhouse. In 1884, he contacted a showman named Sam Torr and proposed that he might be exhibited. Torr arranged for a group of men to manage Merrick, whom they named "the Elephant Man". After touring the East Midlands, Merrick travelled to London to be exhibited in a penny gaff shop rented by showman Tom Norman. The shop was visited by surgeon Frederick Treves, who invited Merrick to be physically examined. Merrick was displayed by Treves at a meeting of the Pathological Society of London in 1884, after which Norman's shop was closed by the police. Merrick then joined Sam Roper's circus and then toured in Europe by an unknown manager. (Full article...)
• 

  

  
  Folate, also known as vitamin B₉ and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as a dietary supplement and in food fortification as it is more stable during processing and storage. Folate is required for the body to make DNA and RNA and metabolise amino acids necessary for cell division and maturation of blood cells. As the human body cannot make folate, it is required in the diet, making it an essential nutrient. It occurs naturally in many foods. The recommended adult daily intake of folate in the U.S. is 400 micrograms from foods or dietary supplements.
  
  
  Folate in the form of folic acid is used to treat anemia caused by folate deficiency. Folic acid is also used as a supplement by women during pregnancy to reduce the risk of neural tube defects (NTDs) in the baby. NTDs include anencephaly and spina bifida, among other defects. Low levels in early pregnancy are believed to be the cause of more than half of babies born with NTDs. More than 80 countries use either mandatory or voluntary fortification of certain foods with folic acid as a measure to decrease the rate of NTDs. Long-term supplementation with relatively large amounts of folic acid is associated with a small reduction in the risk of stroke and an increased risk of prostate cancer. There are concerns that large amounts of supplemental folic acid can hide vitamin B₁₂ deficiency. (Full article...)
• 

  

  
  Martha Maria "Mattie" Hughes Cannon (July 1, 1857 – July 10, 1932) was a British-American politician, physician, Utah women's rights advocate, suffragist, and a polygamous wife engaged in polygyny. Her family immigrated to the United States as converts to the Church of Jesus Christ of Latter-day Saints (LDS Church) and traveled West to settle in the Utah territory with other church members. She started working at the age of fourteen, and at sixteen she enrolled in the University of Deseret (now called the University of Utah), receiving a bachelor's degree in Chemistry. She later attended the University of Michigan and received an M.D.. She became the fourth of six wives in a polygamous marriage to Angus M. Cannon, a prominent Latter-day Saint leader during the anti-polygamy crusade. Cannon exiled herself to Europe so she wouldn't have to testify against her husband and others. Upon returning to Utah, Cannon worked as a doctor and fought for women's rights. She helped put women enfranchisement into Utah's constitution when it was granted statehood in 1896. On November 3, 1896, Cannon became the first female state senator elected in the United States, defeating her own husband, who was also on the ballot. Cannon was the author of Utah sanitation laws and was a founder and member of Utah's first State Board of Health. (Full article...)
• 
  
  

  

  A representation of the molecular surface of one variant of human rhinovirus

  
  The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx. Signs and symptoms may appear in as little as two days after exposure to the virus. These may include coughing, sore throat, runny nose, sneezing, headache, and fever. People usually recover in seven to ten days, but some symptoms may last up to three weeks. Occasionally, those with other health problems may develop pneumonia.
  
  
  Well over 200 virus strains are implicated in causing the common cold, with rhinoviruses, coronaviruses, adenoviruses and enteroviruses being the most common. They spread through the air or indirectly through contact with objects in the environment, followed by transfer to the mouth or nose. Risk factors include going to child care facilities, not sleeping well, and psychological stress. The symptoms are mostly due to the body's immune response to the infection rather than to tissue destruction by the viruses themselves. The symptoms of influenza are similar to those of a cold, although usually more severe and less likely to include a runny nose. (Full article...)
• 
  Constance Virginia Kies (December 13, 1934 – November 30, 1993) was an American nutrition scientist and dietitian. Kies worked as a public school teacher for three years before going against the traditional gender norms of her time and completing an M.S. and Ph.D. from the University of Wisconsin–Madison. Over the duration of her 30-year career at the University of Nebraska–Lincoln, Kies researched nutritional biochemistry. She demonstrated relationships between minerals, proteins, and dietary fiber through pioneering human subject research. Her findings led to advancements in human knowledge of copper and protein metabolism. She was honored with the Borden Award and was a fellow of the American College of Nutrition. Kies was a feminist and a member of the National Organization for Women and the Women's Equity Action League. She died of uterine cancer three months after her diagnosis. (Full article...)

Did you know –

• ...infantile pyloric stenosis is a not uncommon pediatric condition where there is a congenital narrowing of the pylorus (the opening at the lower end of the stomach)? Babies with this condition usually present within the first few weeks (usually between 2nd and 3rd) of life with poor feeding, weight loss and progressively worsening vomiting leading ultimately to projectile non-bilious vomiting.

• ...the Cotard delusion (or Cotard's syndrome, le délire de négation) is a rare disorder in which a person holds a delusional belief that he is dead, does not exist, is putrefying or has lost his blood or internal organs?
• ...the nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to a group of medicines called monoclonal antibodies. This scheme is used for both the World Health Organization’s International Nonproprietary Names and the United States Adopted Names. In general, suffixes are used to identify a class of medicines; all monoclonal antibody pharmaceuticals end with the suffix -mab. However, different infixes are used depending on the structure and function of the medicine.

General images –

The following are images from various Medicine-related articles on Wikipedia.

• 
  "More Doctors Smoke Camels than Any Other Cigarette" advertisement for Camel cigarettes in the 1940s (from Medical ethics)
• 
  Health Expenditure per capita (in PPP-adjusted US$) among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Health spending by country. Percent of GDP (Gross domestic product). For example: 11.2% for Canada in 2022. 16.6% for the United States in 2022. (from Health care)
• 
  Life expectancy vs healthcare spending of rich OECD countries. US average of $10,447 in 2018. (from Health care)
• 
  Replica of Antonie van Leeuwenhoek's microscope of the 1670s (from History of medicine)
• 
  Guy's Hospital in 1820 (from History of medicine)
• 
  A Ukrainian monument to the HIV pandemic. (from History of medicine)
• 
  The plinthios brochos as described by Greek physician Heraklas, a sling for binding a fractured jaw. These writings were preserved in one of Oribasius' collections. (from History of medicine)
• 
  Botánicas such as this one in Jamaica Plain, Boston, cater to the Latino community and sell folk medicine alongside statues of saints, candles decorated with prayers, lucky bamboo, and other items. (from Traditional medicine)
• 
  Medicine during the First World War - Medical Transport. (from History of medicine)
• 
  Charite in Berlin (from History of medicine)
• 
  Jackson Memorial Hospital in Miami, the primary teaching hospital of the University of Miami's Miller School of Medicine and the largest hospital in the United States with 1,547 beds (from Health care)
• 
  American Civil War hospital at Gettysburg, 1863 (from History of medicine)
• 
  AMA Code of Medical Ethics (from Medical ethics)
• 
  Medical personnel place sterilized covers on the arms of the daVinci Xi surgical system, a minimally-invasive robotic surgery system, at the William Beaumont Army Medical Center. (from History of medicine)
• 
  National Hospital for Neurology and Neurosurgery in London, United Kingdom is a specialist neurological hospital. (from Health care)
• 
  A cochlear implant is a common kind of neural prosthesis, a device replacing part of the human nervous system. (from History of medicine)
• 
  A doctor checks a patient's pulse in Meiji-era Japan. (from History of medicine)
• 
  Patient, Surrey County Lunatic Asylum, c. 1850–58. The asylum population in England and Wales rose from 1,027 in 1827 to 74,004 in 1900. (from History of medicine)
• 
  "Diagram of the causes of mortality in the army in the East" by Florence Nightingale. (from History of medicine)
• 
  Hospital train "Therapist Matvei Mudrov" in Khabarovsk, Russia (from Health care)
• 
  The emergency room is often a frontline venue for the delivery of primary medical care. (from Health care)
• 
  Seven named physicians and botanists of the Classical world from Vienna Dioscurides. Clockwise from top center: Galen, Dioscorides, Nicander, Rufus of Ephesus, Andreas of Carystus, Apollonius Mus or of Pergamon, Crateuas (from History of medicine)
• 
  Smallpox vaccination in Niger, 1969. A decade later, this was the first infectious disease to be eradicated. (from History of medicine)
• 
  Sometimes traditional medicines include parts of endangered species, such as the slow loris in Southeast Asia. (from Traditional medicine)
• 
  Hippocrates (c. 460–370 BCE). Known as the "father of medicine". (from History of medicine)
• 
  The Edwin Smith Surgical Papyrus, written in the 17th century BCE, contains the earliest recorded reference to the brain. New York Academy of Medicine. (from History of medicine)
• 
  The Quaker-run York Retreat, founded in 1796, gained international prominence as a centre for moral treatment and a model of asylum reform following the publication of Samuel Tuke's Description of the Retreat (1813). (from History of medicine)
• 
  healthcare expenditure in Japan by age group (from Health insurance)
• 
  Galen (129–216 CE), known for his wide insights into anatomy. (from History of medicine)
• 
  A cuneiform terracotta tablet describing a medicinal recipe for poisoning (c. 18th century BCE). Discovered in Nippur, Iraq.
• 
  Life Expectancy of the total population at birth among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Ethical prayer for medical wisdom by Dr Edmond Fernandes (from Medical ethics)
• 
  A Neo-Assyrian cuneiform tablet fragment describing medical text (c. 9th to 7th century BCE). (from History of medicine)
• 
  18th-century medical remedies collected by a British Gentry family (from History of medicine)
• 
  Statue of Robert Koch, father of medical bacteriology, at Robert-Koch-Platz (Robert Koch square) in Berlin (from History of medicine)
• 
  Total healthcare cost per person. Public and private spending. US dollars PPP. For example: $6,319 for Canada in 2022. $12,555 for the US in 2022. (from Health care)
• 
  Most countries have seen a tremendous increase in life expectancy since 1945. However, in southern Africa, the HIV epidemic beginning around 1990 has eroded national health. (from History of medicine)
• 
  An American billing clerk preparing a detailed invoice. (1992) (from Medical billing)
• 
  Mandrake (written 'ΜΑΝΔΡΑΓΟΡΑ' in Greek capitals). Naples Dioscurides, 7th century (from History of medicine)
• 
  Emil Kraepelin (1856–1926), the founder of modern scientific psychiatry, psychopharmacology and psychiatric genetics. (from History of medicine)
• 
  Traditional medicine in a market in Antananarivo, Madagascar (from Traditional medicine)
• 
  American combat surgery during the Pacific War, 1943 (from History of medicine)
• 
  Taoist symbol of Yin and Yang (from Medical ethics)
• 
  Curandera performing a limpieza in Cuenca, Ecuador (from Traditional medicine)
• 
  Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report. (from Health care)
• 
  Magical stela or cippus of Horus inscribed with healing encantations (c. 332 to 280 BCE). (from History of medicine)
• 
  Louis Pasteur experimenting on bacteria, c. 1870 (from History of medicine)
• 
  Mexico City epidemic of 1737, with elites calling on the Virgin of Guadalupe (from History of medicine)
• 
  Infographic showing how healthcare data flows within the billing process (from Medical billing)
• 
  Zhang Zhongjing – a Chinese pharmacologist, physician, inventor, and writer of the Eastern Han dynasty. (from History of medicine)
• 
  Depiction of smallpox in Franciscan Bernardino de Sahagún's history of the conquest of Mexico, Book XII of the Florentine Codex, from the defeated Aztecs' point of view (from History of medicine)
• 
  Yarrow, a medicinal plant found in human-occupied caves in the Upper Palaeolithic period. (from History of medicine)
• 
  A 12th-century Byzantine manuscript of the Hippocratic Oath (from Medical ethics)
• 
  COVID-19 swab testing in Rwanda (2021). (from History of medicine)
• 
  Sketch of Muslim physician Muhammad ibn Zakariya al-Razi (from History of medicine)
• 
  The numbers of Americans lacking health insurance and the uninsured rate from 1987 to 2008 (from Health insurance)
• 
  A 12th-century manuscript of the Hippocratic Oath in Greek, one of the most famous aspects of classical medicine that carried into later eras (from History of medicine)
• 
  Primary care may be provided in community health centers. (from Health care)

More Did you know (auto generated)

• ... that a lack of screening for pregnant women with syphilis in sub-Saharan Africa is associated with increased infant mortality?
• ... that Constance Fozzard was told during her surgical training that women with children could not become consultants?
• ... that Tang Zonghai was one of the first advocates for the integration of Chinese and Western medicine?
• ... that the Noongar used the Eucalyptus wandoo tree as a medicine and ointment?
• ... that fourteenth-century Buddhist monk Tuệ Tĩnh is referred to as a founding father of traditional Vietnamese medicine?
• ... that Margaret C. Roberts was encouraged to study medicine by LDS Church leader Brigham Young to reduce mortality rates during childbirth?

Topics

Categories

• Medicine

Category puzzle

Select [►] to view subcategories

Medicine

Medicine by city

Medicine by country

Medicine by country subdivision

Medicine by dependent territory

Medicine by century

Medicine by decade

Medicine by year

Alternative medicine

Clinical medicine

Veterinary medicine

Medical lists

Works about medicine

Medical activism

Medical associations

Medicine awards

Cause (medicine)

Chemicals in medicine

Health-related conspiracy theories

Medical aspects of death

Medical diplomacy

Medical education

History of medicine

Medical humanities

Intersex and medicine

Medical and health organizations

Medical phenomena

Practice of medicine

Prescription of drugs

Medical prevention

Religion and medicine

Medical research

Medicine in society

Medical symbols

Medical technology

Medical terminology

Theory of medicine

Medical volunteerism

Women in medicine

Medicine stubs

• Health
  Clinical research
• Disability
• Diseases and disorders
• Therapy

• Biology
  Anatomy
• Biological engineering
• Bioethics
• Cell biology
• Microbiology
• Physiology

Recognized content

Associated Wikimedia

The following Wikimedia Foundation sister projects provide more on this subject:

• 

  Commons
  Free media repository

• 

  Wikibooks
  Free textbooks and manuals

• 

  Wikidata
  Free knowledge base

• 

  Wikinews
  Free-content news

• 

  Wikiquote
  Collection of quotations

• 

  Wikisource
  Free-content library

• 

  Wikiversity
  Free learning tools

• 

  Wiktionary
  Dictionary and thesaurus

Discover Wikipedia using portals

• 

  List of all portals

• 

  The arts portal

• 

  Biography portal

• 

  Current events portal

• 

  Geography portal

• 

  History portal

• 

  Mathematics portal

• 

  Science portal

• 

  Society portal

• 

  Technology portal

• 

  Random portal

• 

  WikiProject Portals