Jump to content

PRPF40A

From Wikipedia, the free encyclopedia
(Redirected from PRPF40A (gene))

PRPF40A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPRPF40A, FBP-11, FBP11, FLAF1, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40, pre-mRNA processing factor 40 homolog A
External IDsOMIM: 612941; MGI: 1860512; HomoloGene: 6377; GeneCards: PRPF40A; OMA:PRPF40A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018785

RefSeq (protein)
Location (UCSC)Chr 2: 152.65 – 152.72 MbChr 2: 53.13 – 53.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pre-mRNA-processing factor 40 homolog A is a protein that in humans is encoded by the PRPF40A gene.[5][6][7]

Interactions

[edit]

PRPF40A has been shown to interact with Huntingtin.[8]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196504Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061136Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Bedford MT, Reed R, Leder P (September 1998). "WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif". Proc Natl Acad Sci U S A. 95 (18): 10602–7. Bibcode:1998PNAS...9510602B. doi:10.1073/pnas.95.18.10602. PMC 27941. PMID 9724750.
  6. ^ Wiesner S, Stier G, Sattler M, Macias MJ (December 2002). "Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40". J Mol Biol. 324 (4): 807–22. doi:10.1016/S0022-2836(02)01145-2. PMID 12460579.
  7. ^ "Entrez Gene: PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)".
  8. ^ Faber PW, Barnes G T, Srinidhi J, Chen J, Gusella J F, MacDonald M E (September 1998). "Huntingtin interacts with a family of WW domain proteins". Hum. Mol. Genet. 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. ISSN 0964-6906. PMID 9700202.

Further reading

[edit]