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POLR2K

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(Redirected from POLR2K (gene))

POLR2K
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPOLR2K, ABC10-alpha, RPABC4, RPB10alpha, RPB12, RPB7.0, hRPB7.0, hsRPB10a, polymerase (RNA) II subunit K, RNA polymerase II subunit K, RNA polymerase II, I and III subunit K
External IDsOMIM: 606033; MGI: 102725; HomoloGene: 86049; GeneCards: POLR2K; OMA:POLR2K - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005034

NM_001039368
NM_023127

RefSeq (protein)

NP_005025

NP_001034457
NP_075616

Location (UCSC)Chr 8: 100.15 – 100.15 MbChr 15: 36.17 – 36.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DNA-directed RNA polymerases I, II, and III subunit RPABC4 is a protein that in humans is encoded by the POLR2K gene.

This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases.[5]

Interactions

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POLR2K has been shown to interact with POLR2C.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147669Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045996Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa".
  6. ^ Acker J, de Graaff M, Cheynel I, Khazak V, Kedinger C, Vigneron M (July 1997). "Interactions between the human RNA polymerase II subunits". The Journal of Biological Chemistry. 272 (27): 16815–21. doi:10.1074/jbc.272.27.16815. PMID 9201987.

Further reading

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