Neamine
Appearance
(Redirected from Neomycin A)
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Other names | Neomycin A |
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Formula | C12H26N4O6 |
Molar mass | 322.362 g·mol−1 |
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Neamine (neomycin A) is a degradation product of the aminoglycoside antibiotic neomycin.[1] Several derivatives of neamine are active against susceptible and resistant Gram-positive and Gram-negative bacteria.[2]
References
[edit]- ^ Leach BE, Teeters CM (June 1951). "Neamine, an Antibacterial Degradation Product of Neomycin". Journal of the American Chemical Society. 73 (6): 2794–2797. doi:10.1021/ja01150a107.
- ^ Zimmermann L, Bussière A, Ouberai M, Baussanne I, Jolivalt C, Mingeot-Leclercq MP, et al. (October 2013). "Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues". Journal of Medicinal Chemistry. 56 (19): 7691–7705. doi:10.1021/jm401148j. PMID 24083676.