narK RNA motif
 |
| narK | |
|---|---|
 Consensus secondary structure and sequence conservation of narK RNA | |
| Identifiers | |
| Symbol | narK |
| Rfam | RF03032 |
| Other data | |
| RNA type | Cis-reg |
| SO | SO:0005836 |
| PDB structures | PDBe |
The narK RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] narK motif RNAs are found in Beta- and Gammaproteobacteria.
narK RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. Four genes are presumably regulated by narK RNA, and they encode: a nitrate transporter, proteins with sulfite- and nitrate reductase domains, proteins in the major facilitator superfamily and cyclic di-GMP-specific phosphodiesterases of the EAL family. It was therefore proposed[1] that there is good evidence that narK RNAs regulate genes in cis, and that they might play a role related to nitrate.
References
[edit]- ^ a b Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.