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NEURL2

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NEURL2
Identifiers
AliasesNEURL2, C20orf163, OZZ, OZZ-E3, neuralized E3 ubiquitin protein ligase 2
External IDsOMIM: 608597; MGI: 3043305; HomoloGene: 15435; GeneCards: NEURL2; OMA:NEURL2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080749
NM_001278535

NM_001082974

RefSeq (protein)

NP_001265464
NP_542787

NP_001076443

Location (UCSC)Chr 20: 45.89 – 45.89 MbChr 2: 164.67 – 164.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neuralized-like protein 2 is a protein that in humans is encoded by the NEURL2 gene.[5][6]

Function

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This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely the adaptor component of the E3 ubiquitin ligase complex in striated muscle, and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124257Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039873Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ (Jun 2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem Sci. 27 (5): 235–41. doi:10.1016/S0968-0004(02)02085-6. PMID 12076535.
  6. ^ a b "Entrez Gene: NEURL2 neuralized homolog 2 (Drosophila)".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.