3-Maleylpyruvic acid
Appearance
(Redirected from Maleylpyruvate)
Names | |
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Preferred IUPAC name
(2Z)-4,6-Dioxohept-2-enedioic acid | |
Identifiers | |
3D model (JSmol)
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1725756 | |
ChEBI | |
ChemSpider | |
KEGG | |
PubChem CID
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Properties | |
C7H6O6 | |
Molar mass | 186.119 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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3-Maleylpyruvic acid, or 3-maleylpyruvate, is a dicarboxylic acid formed by the oxidative ring opening of gentisic acid by gentisate 1,2-dioxygenase during the metabolism of tyrosine.[1] It is converted into 3-fumarylpyruvate by maleylpyruvate isomerase.[2]
References
[edit]- ^ Sugiyama S, Yano K, Komagata K, Arima K (1960). "Metabolites of aromatic compounds by microbes. Part VII. Gentisic acid oxidase". Bull. Agric. Chem. Soc. Jpn. 24: 243–248.
- ^ Lack L (1961). "Enzymic cis-trans isomerization of maleylpyruvic acid". J. Biol. Chem. 236 (11): 2835–2840. doi:10.1016/S0021-9258(19)76386-8. PMID 14461395.