X-linked hypertrichosis
(Redirected from Macias Flores Garcia Cruz Rivera syndrome)
| X-linked hypertrichosis | |
|---|---|
| Other names | X-linked congenital generalized hypertrichosis |
 | |
| X-linked hypertrichosis is an X-linked dominant disorder. | |
| Specialty | Dermatology |
X-linked hypertrichosis, also known as X-linked congenital generalized hypertrichosis, is a hereditary disorders characterized by generalized congenital hypertrichosis and thick eyebrows.[1]
Signs and symptoms
[edit]Hypertrichosis is characterized as excessive hair growth anywhere on the body, in either men or women.[2] X-linked hypertrichosis affects males more than females.[3]
Causes
[edit]X-linked hypertrichosis was first mapped in chromosome Xq24-q27.1 in a Mexican family; however, the underlying genetic facts remain unknown.[4] X-linked hypertrichosis is inherited in an X-linked dominant pattern of inheritance.[3]
See also
[edit]Further reading
[edit]- DeStefano, Gina M.; Fantauzzo, Katherine A.; Petukhova, Lynn; Kurban, Mazen; Tadin-Strapps, Marija; Levy, Brynn; Warburton, Dorothy; Cirulli, Elizabeth T.; Han, Yujun; Sun, Xiaoyun; Shen, Yufeng; Shirazi, Maryam; Jobanputra, Vaidehi; Cepeda-Valdes, Rodrigo; Cesar Salas-Alanis, Julio; Christiano, Angela M. (2013-05-07). "Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis". Proceedings of the National Academy of Sciences. 110 (19): 7790–7795. doi:10.1073/pnas.1216412110. ISSN 0027-8424. PMC 3651487. PMID 23603273.
- Figuera, Luis E.; Pandolfo, Massimo; Dunne, Patrick W.; Cantú, Jose M.; Patel, Pragna I. (1995). "Mapping of the congenital generalized hypertrichosis locus to chromosome Xq24–q27.1". Nature Genetics. 10 (2). Springer Science and Business Media LLC: 202–207. doi:10.1038/ng0695-202. ISSN 1061-4036. PMID 7663516.
External links
[edit]References
[edit]- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1008. ISBN 978-1-4160-2999-1.
- ^ Saleh, Dahlia; Yarrarapu, Siva Naga S.; Cook, Christopher (2023-08-16). "Hypertrichosis". StatPearls Publishing. PMID 30521275. Retrieved 2024-04-27.
- ^ a b Macías-Flores, M. A.; García-Cruz, D.; Rivera, H.; Escobar-Luján, M.; Melendrez-Vega, A.; Rivas-Campos, D.; Rodríguez-Collazo, F.; Moreno-Arellano, I.; Cantu, J. M. (1984). "A new form of hypertrichosis inherited as an X-linked dominant trait". Human Genetics. 66 (1): 66–70. doi:10.1007/BF00275189. ISSN 0340-6717.
- ^ Zhu, Hongwen; Shang, Dandan; Sun, Miao; Choi, Sunju; Liu, Qing; Hao, Jiajie; Figuera, Luis E.; Zhang, Feng; Choy, Kwong Wai; Ao, Yang; Liu, Yang (2011-06-10). "X-Linked Congenital Hypertrichosis Syndrome Is Associated with Interchromosomal Insertions Mediated by a Human-Specific Palindrome near SOX3". American Journal of Human Genetics. 88 (6): 819–826. doi:10.1016/j.ajhg.2011.05.004. ISSN 0002-9297. PMC 3113246. PMID 21636067.