MIR1250

MIR1250
Identifiers
Aliases	MIR1250, MIRN1250, hsa-mir-1250, mir-1250, microRNA 1250
External IDs	GeneCards: MIR1250; OMA:MIR1250 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,133,308 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; blood; ; pituitary gland; ; body of pancreas; ; anterior pituitary; ; olfactory zone of nasal mucosa; ; right frontal lobe; ; prefrontal cortex; ; Brodmann area 9; ; granulocyte;
	n/a
	More reference expression data
	n/a
Orthologs
	100302229
	n/a
	ENSG00000221025
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

MicroRNA 1250 is a protein that in humans is encoded by the MIR1250 gene. ^[3]

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000221025 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: MicroRNA 1250". Retrieved 2018-03-22.

Function

References

Further reading