Leucine rich repeat containing 3

LRRC3
Identifiers
Aliases	LRRC3, C21orf102, leucine rich repeat containing 3, LRRC3DN, C21orf30
External IDs	OMIM: 617620; MGI: 2447899; HomoloGene: 12789; GeneCards: LRRC3; OMA:LRRC3 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	44,462,196 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	77,738,370 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; ganglionic eminence; ; muscle layer of sigmoid colon; ; ventricular zone; ; testicle; ; Descending thoracic aorta; ; ascending aorta; ; gastric mucosa; ; apex of heart; ; fundus;
	Top expressed in
	lumbar spinal ganglion; ; left lobe of liver; ; internal carotid artery; ; external carotid artery; ; urethra; ; supraoptic nucleus; ; right kidney; ; substantia nigra; ; yolk sac; ; proximal tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; protein kinase inhibitor activity;
Cellular component	membrane; integral component of membrane; cytoplasm;
Biological process	negative regulation of protein kinase activity; cytokine-mediated signaling pathway; negative regulation of receptor signaling pathway via JAK-STAT;
	Sources:Amigo / QuickGO
Orthologs
	81543
	237387
	ENSG00000160233
	ENSMUSG00000051652
	Q9BY71
	P59034
	NM_030891
	NM_145152
	NP_112153
	NP_660134
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine rich repeat containing 3 is a protein that in humans is encoded by the LRRC3 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000160233 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051652 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Leucine rich repeat containing 3". Retrieved 2016-05-12.