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INHBC

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INHBC
Identifiers
AliasesINHBC, IHBC, inhibin beta C, inhibin beta C subunit, inhibin subunit beta C
External IDsOMIM: 601233; MGI: 105932; HomoloGene: 21142; GeneCards: INHBC; OMA:INHBC - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005538

NM_010565

RefSeq (protein)

NP_005529

NP_034695

Location (UCSC)Chr 12: 57.43 – 57.45 MbChr 10: 127.19 – 127.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Inhibin beta C chain is a protein that in humans is encoded by the INHBC gene.[5][6]

This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000175189Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025405Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ H tten G, Neidhardt H, Schneider C, Pohl J (Feb 1995). "Cloning of a new member of the TGF-beta family: a putative new activin beta C chain". Biochem Biophys Res Commun. 206 (2): 608–13. doi:10.1006/bbrc.1995.1086. PMID 7826378.
  6. ^ a b "Entrez Gene: INHBC inhibin, beta C".

Further reading

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