Immunoglobulin superfamily member 3

IGSF3
Identifiers
Aliases	IGSF3, EWI-3, V8, LCDD, immunoglobulin superfamily member 3
External IDs	OMIM: 603491; MGI: 1926158; HomoloGene: 1182; GeneCards: IGSF3; OMA:IGSF3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	116,667,755 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	101,370,375 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; tibia; ; ganglionic eminence; ; vulva; ; hair follicle; ; middle temporal gyrus; ; placenta; ; ventricular zone; ; oral cavity; ; renal medulla;
	Top expressed in
	cumulus cell; ; hand; ; superior cervical ganglion; ; molar; ; endocardial cushion; ; oocyte; ; secondary oocyte; ; primary oocyte; ; zygote; ; sexually immature organism;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	membrane; cell surface; plasma membrane; integral component of membrane;
Biological process	lacrimal gland development; cell surface receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3321
	78908
	ENSG00000143061
	ENSMUSG00000042035
	O75054
	Q6ZQA6
	NM_001007237; NM_001542
	NM_207205
	NP_001007238; NP_001533
	NP_997088; NP_001391335; NP_001391336; NP_001391337
	Wikidata
View/Edit Human	View/Edit Mouse

Immunoglobulin superfamily member 3 is a protein that in humans is encoded by the IGSF3 gene. ^[5]

Function

The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains. A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD). [provided by RefSeq, Jun 2016].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143061 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042035 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Immunoglobulin superfamily member 3". Retrieved 2018-10-06.

Function

References

Further reading