Tripterygium regelii
| Tripterygium regelii | |
|---|---|
| |
Scientific classification 
| |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Rosids |
| Order: | Celastrales |
| Family: | Celastraceae |
| Genus: | Tripterygium |
| Species: | T. regelii
|
| Binomial name | |
| Tripterygium regelii Sprag. & Takeda
| |
Tripterygium regelii, or Regel's threewingnut (Pinyin: Dōngběi léigōng téng),[1] is a rambling, shrubby perennial deciduous yellow vine native to Korea, Japan and Manchuria. It grows to about 200 centimetres (79 in). Small very pretty yellowish white or white flowers appear in May–June and are produced on 203–229 millimetres (8.0–9.0 in). long panicles, and smell somewhat of new-mown hay. Fruits are greenish white, 3-angled, and winged.[2][3]
"Tripterygium wilfordii Hook.f., known as Leigongteng (Thunder God Vine) in traditional Chinese medicine, has attracted much attention for its applications in relieving autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus, and for treating cancer. Molecular analyses of the ITS and 5S rDNA sequences indicate that T. hypoglaucum and T. doianum are not distinct from T. wilfordii, while T. regelii should be recognized as a separate species. The results also demonstrate potential value of rDNA sequence data in forensic detection of adulterants derived from Celastrus angulatus in commercial samples of Leigongteng."[4]
Pharmacology
[edit]Tripterygium regelii is listed as a poisonous plant in the U.S. Food and Drug Administration Poisonous Plant Database.[5]
Certain extracts from Tripterygium wilfordii, as well as from T. hypoglaucum (now synonymous with T. regelii) and Tripterygium regelii, were discovered in the 1980s to have temporary antifertility effects, which has led to research on its potential as a contraceptive.[citation needed]
Chemical compounds called hypoglaunines can be isolated from the bark of T. regelii.[6] Hypoglaunine B is a sesquiterpene alkaloid that is a macrolide incorporating a substituted pyridine and dihydroagarofuran moieties. It exhibits anti-HIV activity in vitro.[7][8]
Footnotes
[edit]- ^ Law et al (2010), p. 21.
- ^ "Tripterygium regelii". Backyard Gardener. Retrieved April 11, 2011.
- ^ "Tripterygium regelii". Plant Supplies. Archived from the original on March 21, 2012. Retrieved April 11, 2011.
- ^ Law et al (2010), p. 21.
- ^ GuangSheng, D. "Important Chinese herbal remedies". FDA Poisonous Plant Database. Retrieved April 11, 2011.
- ^ Xie FG, Li CJ, Yang JZ, Luo YM, Zhang DM (2012). "[data missing]" [Study on chemical constituents from the root bark of Tripterygium hypoglaucum]. Zhong Yao Cai (in Chinese). 35 (7): 1083–1087. PMID 23252270.
- ^ Hongquan Duana; Yoshihisa Takaishi; Masahiko Bando; Masaru Kido; Yasuo Imakura; Kuo Hsiung Lee (1999). "Novel sesquiterpene esters with alkaloid and monoterpene and related compounds from Tripterygium hypoglaucum: A new class of potent anti-HIV agents". Tetrahedron Letters. 40 (15): 2969–2972. doi:10.1016/S0040-4039(99)00339-1.
- ^ Hypoglaunine B at ebi.ac.uk
References
[edit]- [1] Downloadable PDF - "Molecular analyses of the Chinese herb Leigongteng (Tripterygium wilfordii Hook.f.)" (2010). Sue Ka-Yee Law et al. Phytochemistry 72 (2011) 21–26, Elsevier.